Encicarb 50mg Injection

Composition Ferric Carboxymaltose (50mg/ml)
Rx Prescription Required
Pack vial of 10 ml Injection
Storage Store below 30°C
Chemical Class Iron Carbohydrate Complex
Action Class Hemopoietic Agents
Habbit Forming
Manufacturer Emcure Pharmaceuticals Ltd
Manufacturer address 255/2, Hinjawadi, Pune – 411057, India

Encicarb 50mg Injection is an iron replacement medicine. It is used to treat a type of anemia where you have fewer amount of red blood cells due to insufficient iron in your body (iron-deficiency anemia). Iron is needed to produce the red blood cells that carry oxygen around your body.

Encicarb 50mg Injection is given by injection or infusion (saline drip) into a vein by your doctor or nurse. You will be watched carefully to make sure you do not have an allergic reaction. It is usually given in two doses, seven days apart. Your doctor will decide how much and how often you may need injections to improve your anemia. Eating a well-balanced diet that has enough iron, vitamins, and minerals can help to replenish your iron reserves. Good sources of iron include meat, eggs, raisins, broccoli, and lentils. 
The most common side effects include vomiting, headache, dizziness, high blood pressure, and pain or irritation at the site of injection. Most of these usually go away within a short time of the injection. If you are bothered by them or they go on for longer, talk to your doctor or nurse. You should not have this medicine if your anemia is not caused by a lack of iron. 
Before taking it, tell your doctor if you have rheumatoid arthritis, asthma or other allergies, high blood pressure, or liver problems. This may affect your treatment. It is not known whether this medicine is safe for use if you are pregnant or breastfeeding so please take advice from your doctor. You will have tests to check your blood cells and iron levels, monitor your progress, and check for side effects. It may be advisable to limit alcohol during treatment.

Iron deficiency anemia

Anemia due to chronic kidney disease

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Encicarb 50mg Injection is an anti-anemic medication. It replenishes the iron stores in your body. Iron is vital for the formation of new red blood cells and hemoglobin, a substance that gives these cells the ability to transport oxygen.

Q: What if you forget to take Encicarb Injection?
A: If you miss a dose of Encicarb 50mg Injection, please consult your doctor.

Encicarb 50mg Injection is used for the treatment of iron deficiency, when oral iron preparations are ineffective or cannot be used.

Your doctor or nurse will administer it by injection. You will be observed for at least 30 minutes after each injection as it may cause allergic reaction.

Your blood pressure and blood iron levels will be regularly monitored during treatment with this medication.

Inform your doctor if you are taking any iron-containing products by mouth.

Do not consume alcohol when on treatment with this medicine as it may worsen its side effects.

It may cause your stools to become black or dark in color. This is normal and harmless.

Q. What precautions are required while administering Encicarb 50mg Injection?

Encicarb 50mg Injection should be administered by staff that is trained in dealing with serious allergic reactions (anaphylactic reaction). Encicarb 50mg Injection can be administered as an undiluted injection, directly into the vein or via a dialyzer if the patient is on dialysis. It can also be diluted with sodium chloride and given as infusion directly into the vein. The patient should be monitored for at least 30 minutes after each injection. Also, the injection should not be given below the skin (subcutaneous route) or in the muscle (intramuscular route).

Q. How should Encicarb 50mg Injection vials be stored before use?

Encicarb 50mg Injection vials should be stored at 20°C to 25°C (68°F to 77°F). Remember, these should not be freezed. The temperature should not deviate more than 15°C to 30°C (59°F to 86°F).

Q. How often can Encicarb 50mg Injection be re-injected?

Usually, two doses of this medicine are given 7 days apart. The hemoglobin is then assessed at least 4 weeks after the final injection to allow time for the RBCs to form. If the reports still show deficiency of iron, it can be re-administered depending on individual need.

Q. Can Encicarb 50mg Injection cause an increase in blood pressure?

Yes, Encicarb 50mg Injection may cause a temporary increase in blood pressure accompanied with facial flushing, dizziness, and nausea. This may occur immediately after you take the medicine and generally disappears within 30 minutes.

Q. What should be done if leakage of Encicarb 50mg Injection occurs?

Incorrect administration of Encicarb 50mg Injection may cause leakage of the medicine at the administration site. The administration must be stopped immediately if there is some leakage. The leakage may cause skin irritation and long-lasting brown discoloration of skin at the administration site.

Q. Is Encicarb 50mg Injection safe in pregnancy?

There is limited data on the use of Encicarb 50mg Injection in pregnancy. It is important to tell your doctor if you are pregnant or are planning to have a baby. Consult your doctor if you become pregnant during treatment with Encicarb 50mg Injection. Your doctor will decide whether you need to continue treatment or discontinue it.

Headache

Dizziness

High blood pressure

Injection site reactions (pain, swelling, redness)

Vomiting

Nausea

Dark colored stool

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Encicarb 50mg Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Encicarb 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Encicarb 50mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving:SAFE

Encicarb 50mg Injection does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Encicarb 50mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Encicarb 50mg Injection may not be needed in these patients. Please consult your doctor.

Liver:CAUTION

Encicarb 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Encicarb 50mg Injection may be needed. Please consult your doctor.

Ferric carboxymaltose. Bagshot Park, Surrey: Vifor Pharma UK Limited; 2007 [revised Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from: View
Ferric Carboxymaltose. 2013. [Accessed 07 Apr. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from: View
Ferric carboxymaltose injection [Prescribing Inforamtion]. Shirley, NY: Regent, Inc.; 2021.[Accessed 25 Jul. 2024] (online) Available from: View