Endogest 400 SR Tablet
Endogest 400 SR Tablet is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.
Endogest 400 SR Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Endogest 400 SR Tablet is a natural female sex hormone, progesterone. It is used to treat menstrual and pregcy-related issues that are caused due to hormonal imbalance.
Endogest 400 SR Tablet is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus). It should be taken with food. It should be taken at the same time each day to get the most benefit. You should continue taking it for as long as your doctor has told you to, even if you feel well.
The most common side effects include abdominal bloating, abdominal pain, dizziness, headache, depression, breast tenderness, hot flushes, vaginal discharge, joint paint, and urinary incontinence. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. You may also experience bleeding or spotting between your periods, consult with your doctor if it happens frequently.
Before taking this medicine, inform your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You will probably have several tests both before and during treatment to check your womb. Also, tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. In general, it is advisable to avoid alcohol and smoking.
03Uses
Hormone replacement therapy
Treatment of Female infertility
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endogest 400 SR Tablet is to be taken with food.
05How It Works
Endogest 400 SR Tablet is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.
06What If You Miss A Dose?
If you miss a dose of Endogest 400 SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However, it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
In Treatment of Female infertility
Endogest 400 SR Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Urinary incontinence
Joint pain
Vaginal discharge
Hot flushes
Breast tenderness
Depression
Dizziness
Abdominal pain
Headache
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Endogest 400 SR Tablet. Please consult your doctor.
Pregnancy:SAFE IF PRESCRIBED
Endogest 400 SR Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding:SAFE IF PRESCRIBED
Endogest 400 SR Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:UNSAFE
Endogest 400 SR Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Endogest 400 SR Tablet in patients with kidney disease. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Endogest 400 SR Tablet in patients with liver disease. Please consult your doctor.
10Drug Tips
Endogest 400 SR Tablet is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
It is used as a part of hormone replacement therapy generally in combination with an estrogen.
It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
It should be taken with food.
It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
References
Sources and references
Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Medscape. Progesterone . view
Progesterone. London, UK: Besins HealthcareLtd.; 2003 . view
Apgar S, Greenberg G. Using Progestins in Clinical Practice. Am Fam Physician. 2000;62:1839-46. view
