Composition Estradiol (1mg) + Sildenafil (25mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30ยฐC
Chemical Class
Action Class
Habbit Forming No
Manufacturer Akumentis Healthcare Ltd
Manufacturer address 204, 2nd Floor, G-Corp Tech Park, Kasarvadavali, Near Hypercity, Ghodbandar Road, Thane (West) – 400615. ,Maharashtra, India

Endothik ES 1mg/25mg Tablet
Endothik ES 1mg/25mg Tablet is a combination of two medicines used to treat various forms of female infertility. It works by replacing the natural hormone (estrogen) in the body and furthermore, widens the blood vessels to increase the blood flow of the uterus.
Basic Info
Description
Endothik ES 1mg/25mg Tablet should be taken with or without food, preferably at a fixed time each day. This is done to ensure consistent levels of medicine in the body. It should be taken as per your doctor’s advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a glass of water. You should take this medicine for as long as it is prescribed for you.
Diarrhea, nausea, stomach pain, and indigestion are some common side effects of this medicine. However, consult with your doctor if menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods happen or bother you. Some serious side effects which mean immediate doctor consultation is required include unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision.
Before taking Endothik ES 1mg/25mg Tablet, tell your doctor if you are breastfeeding, if you have ever had any problems with your blood circulation or have diabetes or stroke. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. It might increase the risk of breast cancer, hence regular breast examination is recommended.
Uses
Female infertility
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Endothik ES 1mg/25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
MOA
Endothik ES 1mg/25mg Tablet is a combination of two hormonal medicines: Estradiol and Sildenafil. Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. It works by replacing the natural hormone in the body when the latter is deficient. Sildenafil is a vasodilator which widens the blood vessels and increases blood flow to the uterus.
What If
If you miss a dose of Endothik ES 1mg/25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Endothik ES 1mg/25mg Tablet helps improve thickness of endometrium in women undergoing treatment for infertility.
Take it at the same time everyday to help you remember to take it.
You may experience menstrual irregularities such as spotting or bleeding between menstrual periods or missed periods. Consult your doctor if this persists.
Ensure that you undergo regular breast screening (for presence of lumps or any abnormal changes) and cervical smear test while taking this medicine.
Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein.
Faqs
Information not available at the moment. Please check back later.
Benifits
In Female infertility
Endothik ES 1mg/25mg Tablet helps in the production and development of healthy eggs in women. This improves fertility in women and increases the chance of pregnancy. Endothik ES 1mg/25mg Tablet also helps increase thickness of the lining of the womb so that the egg can implant if it becomes fertilised. This increases the chance of a successful pregnancy. Overall, Endothik ES 1mg/25mg Tablet improves the function of the female reproductive organs. Take this medicine in the dose and duration prescribed by the doctor.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Pain in extremity
Flushing (sense of warmth in the face, ears, neck and trunk)
Breast pain
Nosebleeds
Headache
Indigestion
Stomach pain
Nausea
Diarrhea
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Endothik ES 1mg/25mg Tablet.
Pregnancy:UNSAFE
Endothik ES 1mg/25mg Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:SAFE IF PRESCRIBED
Endothik ES 1mg/25mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:UNSAFE
Endothik ES 1mg/25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CAUTION
Endothik ES 1mg/25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Endothik ES 1mg/25mg Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Endothik ES 1mg/25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Endothik ES 1mg/25mg Tablet may be needed. Please consult your doctor.Use of Endothik ES 1mg/25mg Tablet is not recommended in patients who previously had liver disease and the liver function tests are still not normal.
Refferences
Ethinylestradiol . Ashton-under-Lyne, England: Recipharm Ltd.; 2019. view

