Enoxasure 40mg/0.4ml Injection

Enoxasure 40mg/0.4ml Injection is an anticoagulant used to prevent and treat harmful blood clots. It stops the existing clots from getting any bigger and restricts the formation of any new clot. It is also helpful in the prevention of blood clots in veins, a condition called deep vein thrombosis, and pulmonary embolism.

Enoxasure 40mg/0.4ml Injection is injected under the skin by a doctor or nurse. It should not be injected into a muscle. The dose and length of treatment are based on your medical condition, your response to the medicine, and what you are being treated for. It may also be based on your age and weight. It is important to keep using this medicine even if you do not notice any symptoms because it is preventing future harm. If you stop taking it, you could get a blood clot. While taking this medicine you should avoid doing things that increase your risk of bleeding or injury.

The most common side effect of this medicine include injection site pain, bleeding, headache, increased blood platelets, breathing problems, edema, anemia, fever, diarrhea, and increased liver enzymes. A severe headache could be a sign of bleeding in the brain. A severe stomach ache could be a sign of bleeding in the stomach. Bleeding can be dangerous and may not be obvious. Look out for symptoms and tell your doctor if you are worried.

Before using this medicine, you should tell your doctor if you have high blood pressure, diabetes, or have had a recent stroke. You should not take it if you have any current bleeding. Some medicines should not be used with Enoxasure 40mg/0.4ml Injection. Tell your doctor what else you are taking to make sure it is safe. If you have low body weight, you may be at increased risk of bleeding, and drinking alcohol can increase the risk of stomach bleeding.

Acute coronary syndrome

Deep vein thrombosis

Pulmonary embolism

Treatment and prevention of Blood clots

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Enoxasure 40mg/0.4ml Injection is an anticoagulant. It works by inactivating certain blood-clotting proteins. This prevents the formation of blood clots and prevents blockages in the blood vessels of the body.

Q: What if you forget to take Enoxasure Injection?
A: If you miss a dose of Enoxasure 40mg/0.4ml Injection, please consult your doctor.n

You have been prescribed Enoxasure 40mg/0.4ml Injection for the treatment and prevention of blood clots.

Enoxasure 40mg/0.4ml Injection increases your risk of bleeding. Be careful while shaving, using sharp objects or cutting fingernails or toenails.

Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs.

Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit.

Do not stop taking the medication suddenly without talking to your doctor.

You have been prescribed Enoxasure 40mg/0.4ml Injection for the treatment and prevention of blood clots.

Unlike other similar medications, regular lab tests are not required.

Enoxasure 40mg/0.4ml Injection increases your risk of bleeding. Be careful while shaving, using sharp objects or cutting fingernails or toenails.

Inform your doctor if you are also taking other medicines that increase the bleeding risk like aspirin and NSAIDs.

Inform your doctor if there is bleeding from gums, nose or wounds that lasts more than 15 minutes or if blood appears in your urine, stool or vomit.

Do not stop taking the medication suddenly without talking to your doctor.

Q. How do you administer Enoxasure 40mg/0.4ml Injection?

Enoxasure 40mg/0.4ml Injection is a medicine which is injected beneath the skin. Fix the dose of the medicine and pinch the skin of your stomach between your finger and thumb to make a fold. After having cleaned the area, hold the syringe like a pencil and insert the full length of the needle into the skin fold. Inject the medicine and discard the syringe as instructed by your prescribing physician. Follow the instructions given by the healthcare provider strictly. Contact your doctor in case of any doubt or any reactions associated with the medicine.

Q. What are the conditions where I should be cautious before taking Enoxasure 40mg/0.4ml Injection?

You must give a proper history to your doctor before you start taking Enoxasure 40mg/0.4ml Injection. Inform your doctor if you have a heart valve fitted or have gastric ulcer, high blood pressure, diabetes, or kidney problems. You should also let your doctor know if you ever had a reaction to heparin or had a recent stroke, brain or spinal surgery. The chances of side effects and complications increase in presence of these conditions. Consult with your doctor and follow the instructions strictly.

Q. How to store Enoxasure 40mg/0.4ml Injection injections?

Store Enoxasure 40mg/0.4ml Injection injections at 25°C and do not freeze them. The multiple-dose vials should not be stored for more than 28 days after the first use. Discard the injection if you notice any particulate matter or abnormal color in the solution or any damage in the syringe. Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt.

Q. Can Enoxasure 40mg/0.4ml Injection be used in heart attack?

Yes, Enoxasure 40mg/0.4ml Injection is used in the treatment of chest pain and heart attack once the standard treatment has been provided to the patient. It is given along with another blood thinner like aspirin. Being a blood-thinning agent, it prevents the blood from clotting and prevents any further episodes and complications.

Q. Is it ok to inject the air bubble in Enoxasure 40mg/0.4ml Injection?

Yes, you should push the air bubbles into the site of injection. Removing the air bubbles leads to loss of the medicine thereby altering the prescribed dose.

In Treatment and prevention of Blood clots

Enoxasure 40mg/0.4ml Injection prevents new blood clots from forming and prevents the existing ones from getting bigger. It works by blocking a substance in the body which is involved in blood clotting. Thus it helps your blood flow smoothly throughout the body. This can help reduce damage caused by clots in your lungs (pulmonary embolism), brain (stroke), heart (heart attack), or other blood vessels (thrombosis). It can also be used to prevent clots from forming after surgery, for example, to replace a knee or hip joint. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It can also make it less likely that parts of a clot will break off and travel to other parts of the body.

Bleeding

Headache

Low blood platelets

Increased liver enzymes

Anemia (low number of red blood cells)

Fever

Injection site pain

Breathing problems

Edema (swelling)

Diarrhea

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Enoxasure 40mg/0.4ml Injection. Please consult your doctor.

Pregnancy:SAFE IF PRESCRIBED

Enoxasure 40mg/0.4ml Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:SAFE IF PRESCRIBED

Enoxasure 40mg/0.4ml Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Enoxasure 40mg/0.4ml Injection is released in small amounts in the breast milk and amounts reaching the baby are also small, which would not be expected to cause any harmful effects to the baby.

Driving:SAFE

Enoxasure 40mg/0.4ml Injection does not usually affect your ability to drive.

Kidney:CAUTION

Enoxasure 40mg/0.4ml Injection should be used with caution in patients with kidney disease. Dose adjustment of Enoxasure 40mg/0.4ml Injection may be needed. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Enoxasure 40mg/0.4ml Injection in patients with liver disease. Please consult your doctor.However, cautious use is advised in patients with underlying liver disease.

Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 373-74.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 471.
Enoxaparin sodium. Guildford, Surrey: SANOFI; 1997 [revised 08 Apr. 2018]. [Accessed 18 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Enoxaparin. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). Enoxaparin. [Accessed 18 Mar. 2019] (online) Available from: View
Enoxaparin [Dosage and Administration Guide]. [Accessed 20 June 2023]. (online) Available from: View
Enoxaparin [Prescribing Information]. Rancho Cucamonga, CA: Amphastar Pharmaceuticals, Inc.; 2023. [Accessed 20 June 2023]. (online) Available from: View