Epofit 10000IU/ml Injection
Epofit 10000IU/ml Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by medicines to treat HIV.
Epofit 10000IU/ml Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Epofit 10000IU/ml Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by medicines to treat HIV.
Epofit 10000IU/ml Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by medicines to treat HIV.
Epofit 10000IU/ml Injection is given by injection either under the skin or into a vein, which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Epofit 10000IU/ml Injection needs to be stored in a fridge but used at room temperature.
The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness, and aches and pains. These side effects are most common at the start of treatment, but if they persist, your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes, this medicine can cause serious blood clots that need urgent medical attention.
Before using Epofit 10000IU/ml Injection, you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (a disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
03Uses
Treatment of Anemia due to cancer chemotherapy
Treatment of Anemia due to chronic kidney disease
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Epofit 10000IU/ml Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
06What If You Miss A Dose?
Q: What if you forget to take Epofit Injection?
A: If you miss a dose of Epofit 10000IU/ml Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Anemia due to cancer chemotherapy
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epofit 10000IU/ml Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.
08Side Effects
Muscle spasm
Dizziness
Vascular occlusion
Injection site irritation
Stomatitis (Inflammation of the mouth)
Weight loss
Decreased white blood cell count (lymphocytes)
Increased glucose level in blood
Blood clot in the blood vessels
High blood pressure
Nausea
Vomiting
Fever
Rash
Joint pain
Headache
Insomnia (difficulty in sleeping)
Chills
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Epofit 10000IU/ml Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Epofit 10000IU/ml Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Epofit 10000IU/ml Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Epofit 10000IU/ml Injection may cause side effects which could affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Epofit 10000IU/ml Injection is safe to use in patients with kidney disease. No dose adjustment of Epofit 10000IU/ml Injection is recommended.Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver:CAUTION
Epofit 10000IU/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Epofit 10000IU/ml Injection may be needed. Please consult your doctor.
10Drug Tips
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, and electrolytes such as potassium in your blood.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure, such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Stop taking Epofit 10000IU/ml Injection and inform your doctor if you develop shortness of breath or a skin rash.
References
Sources and references
Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Leiden, Netherlands: Janssen Biologics B.V; [revised Oct. 2018]. [Accessed 07 Apr. 2019] (online) Available from: View
Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Amgen Inc; 1989 [revised Dec. 2013]. [Accessed 07 Apr. 2019] (online) Available from: View
Epoetin alfa [Prescribing Information]. Horsham, Pennsylvania: Janssen Products, LP; 2017. [Accessed 28 Mar. 2023] (online) Available from: View
Epoetin alfa [Prescribing Information]. Pune, Maharashtra: Emcure Pharmaceuticals Limited; 2024. [Accessed 02 Apr. 2025] (online) Available from: View
Epoetin alfa [Prescribing Information]. Vilbel, Germany: STADA Arzneimittel AG; 2012. [Accessed 02 Apr. 2025] (online) Available from: View
