Composition Chlorpheniramine Maleate (1mg/5ml) + Paracetamol (125mg/5ml) + Phenylephrine (5mg/5ml)
Rx Prescription Required
Pack bottle of 60 ml Syrup
Storage Store below 30ยฐC
Chemical Class
Action Class
Habbit Forming No
Manufacturer Indoco Remedies Ltd
Manufacturer address Indoco Remedies Limited, Indoco House, 166 CST Road, Santacruz (E), Mumbai 400 098, INDIA

Febrex Plus Syrup
Febrex Plus Syrup is commonly prescribed in children to treat symptoms such as runny nose, cough, sneezing, watery eyes, sore throat, body ache, and fever. These symptoms are usually associated with common cold, hay fever (allergic rhinitis), and other respiratory tract conditions.
Basic Info
Description
Give Febrex Plus Syrup to your child by mouth with or without food. If your child develops a stomach upset, prefer giving it with food. Always remember that the dosing schedule provided by your child’s doctor depends on the type of symptoms your child has, so make sure to follow the prescribed dose, time, and way strictly.
Give Febrex Plus Syrup at a fixed time each day so that it gradually makes a place in your child’s daily routine, which will help you to remember. If your child vomits within 30 minutes of taking this medicine give the same dose again. However, never repeat the dose if it’s already time for the next dose. Your child may start to feel better within a week of regular dosing. However, you must continue giving the medicine to your child to finish the complete prescribed course as stopping it abruptly may worsen your child’s condition.
Some of the minor and temporary side effects that your child may experience while taking this medicine include vomiting, diarrhea, nausea, dizziness, rash, and headache. Usually, these episodes subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome for your child, consult your child’s doctor without any delay.
Narrate your child’s complete medical history to your child’s doctor, including any ongoing medicine regime or history of any allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, skin disorder, liver impairment, and kidney malfunction. This information is critical for dose alterations and for planning your child’s overall treatment.
Uses
Treatment of Common cold symptoms
How To Use
Information not available at the moment. Please check back later.
MOA
Febrex Plus Syrup is a combination of four medicines: Chlorpheniramine Maleate, Phenylephrine, Paracetamol, and Sodium Citrate, which relieves common cold symptoms. Chlorpheniramine is an antiallergic that relieves allergy symptoms like runny nose, watery eyes, and sneezing. Phenylephrine is a decongestant that narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Sodium citrate is a mucolytic that thins and loosens mucus (phlegm), making it easier to cough out.
What If
Do not panic. Unless your childโs doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if itโs almost the time for the next dose. Follow the prescribed dosing schedule and do not give a double dose to catch up with the missed dose.
Drug Tips
Febrex Plus Syrup may make your child feel sleepy. Ensure your child takes extra care when taking part in physical activities.
Never combine Febrex Plus Syrup with other cold and flu medicines as that may lead to side effects.
Stop Febrex Plus Syrup and immediately report to the doctor if your child develops an itchy rash, facial swelling, or breathing difficulties.
Practice self-care tips:Clean and disinfect surfaces after sneezing and coughing to avoid allergy.Give your child plenty of fluids as it helps to thin and loosen the mucus accumulated in the lungs.Restrain your child from having caffeinated products and foods that are spicy and fried. All these can trigger coughing.Make your child gargle with warm saltwater.Ensure your child takes enough rest.
Clean and disinfect surfaces after sneezing and coughing to avoid allergy.
Give your child plenty of fluids as it helps to thin and loosen the mucus accumulated in the lungs.
Restrain your child from having caffeinated products and foods that are spicy and fried. All these can trigger coughing.
Make your child gargle with warm saltwater.
Ensure your child takes enough rest.
Faqs
Q. What if I give too much Febrex Plus Syrup by mistake?
Prolonged or excess intake of Febrex Plus Syrup can put your child at risk of developing serious side effects like seizures, rapid heart rate, /depression, cognition defects, and inability to concentrate. Always stick to the prescribed dose. To pour out the right dose, use the calibrated cup provided with the medicine by the manufacturer. Do not use a kitchen teaspoon as it will not give the correct estimate.
Q. Can other medicines be given at the same time as Febrex Plus Syrup?
Febrex Plus Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Febrex Plus Syrup. Also, check with your childโs doctor before giving any medicine to your child.
Q. In what all conditions should I avoid giving Febrex Plus Syrup to my child?
If your child is suffering from any Cardiovascular disease (hypertension, heart disease), Diabetes mellitus, GI obstruction, increased intraocular pressure, urinary obstruction, or thyroid dysfunction, avoid giving Febrex Plus Syrup. Always inform your doctor about your childโs medical history before giving Febrex Plus Syrup.
Q. My child has a cough and fever. Can I give him two different cough and fever medicines together?
Do not give your child more than one cough or cold medicine at a time unless advised by the doctor. This is because both the medicines could have the same ingredients and taking them together would cause an overdose and could result in serious implications on your child. Always consult your childโs doctor before giving any medicine to your child.
Q. Can I give my cough medicine to my child?
Never give your child the medicines that have been recommended for use by adults. Children should only be given the medicines specifically formulated for them, else it may cause unwanted side effects. Check the label of the medicine properly before use in your child. Give the medicine to your child in the prescribed dose specifically. It is best to take your child to the doctor if the symptoms are bothersome or fail to improve even after treatment.
Q. Can Febrex Plus Syrup make my child sleepy?
Febrex Plus Syrup may cause mild drowsiness effect, making your child feel sleepy. So, be cautious and never give this medicine to induce sleep. Forced sleep could mask any underlying sleep disorder like insomnia. Itโs always best to consult your childโs doctor before giving this medicine to your child.
Q. How can I store Febrex Plus Syrup?
Febrex Plus Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all medicines out of the reach and sight of children to avoid any accidental intake.
Benifits
In Treatment of Common cold symptoms
Febrex Plus Syrup is a combination medicine that effectively relieves symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps to loosen thick mucus, making it easier to cough out. This makes it easier for air to move in and out. It shrinks the blood vessels and provides rapid relief that lasts for several hours. Febrex Plus Syrup usually starts to work within a few minutes and the effects can last up to several hours. Take it as prescribed by the doctor. Do not stop using it unless you are advised to by your doctor. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.
Side Effects
Febrex Plus Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, theyโre likely to subside once the body adapts to the medicine. Consult your childโs doctor if these side effects persist or bother your child. The most common side effects include-
Dizziness
Headache
Sleepiness
Allergic reaction
Vomiting
Nausea
Rash
Diarrhea
Safety Profile
Kidney:CAUTION
Febrex Plus Syrup should be used with caution in patients with kidney disease. Dose adjustment of Febrex Plus Syrup may be needed. Please consult your doctor.
Liver:CAUTION
Febrex Plus Syrup should be used with caution in patients with liver disease. Dose adjustment of Febrex Plus Syrup may be needed. Please consult your doctor.
Refferences
Skidgel RA. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC . Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018. p. 718.
Cleveland Clinic. Chlorpheniramine; Dextromethorphan; Phenylephrine oral solution or syrup. view
Drugs.com. Chlorpheniramine, dextromethorphan, and phenylephrine. . view
U.S. National Library of Medicine. Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome. view
Hydrocodone bitartrate and chlorpheniramine maleate . Madison, MS: Hawthorn Pharmaceuticals, Inc.; 2013. view

