Hepadot Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding.
Hepadot Injection is generally administered by a healthcare professional. You should not self administer this medicine. Inform your doctor if you have undergone heart surgery, have had a vasectomy, have diabetes, have received protamine insulin, or allergic to fish.
Using of Hepadot Injection can cause few side effects such as decreasing your blood pressure, slow heart rate, or reactions at the site of injection. It is important to monitor the clotting levels if you are receiving multiple doses or prolonged administration of protamine.
Heparin overdose
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Hepadot Injection is used to counteract the anticoagulant effect of heparin and is used to stop bleeding in patients caused by heparin.
If you miss a dose of Hepadot Injection, please consult your doctor.
Hepadot Injection helps neutralize the effect of anti-clotting medicine heparin.
It should not be used to reverse the effects of other anti-clotting medicines (anticoagulants) such as warfarin.
It should be used under medical supervision. Do not self-administer.
Inform your doctor if you experience a sudden fall in blood pressure, breathlessness, or chest and abdominal pain when receiving Hepadot Injection.
Q. Is protamine sulphate the antidote for lovenox?
Yes. Protamine sulphate is used as an antidote in the case of overdose of lovenox.
Q. Is protamine an anticoagulant?
When administered alone, protamine has an anticoagulant effect. However, when it is given in the presence of heparin, a stable salt is formed and the anticoagulant activity of both drugs is lost
In Heparin overdose
Heparin is an anticoagulant that prevents the formation of blood clots. Heparin overdose is when a person takes more than the normal or recommended amount of heparin. Hepadot Injection helps to control excessive bleeding that takes place due to this high intake of heparin. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully and let your doctor know about any surgeries you may have undergone in the past.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Injection site reactions (pain, swelling, redness)
Slow heart rate
Decreased blood pressure
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Hepadot Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Hepadot Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:SAFE
Hepadot Injection does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Hepadot Injection may not be needed in these patients. Please consult your doctor.
Liver:SAFE IF PRESCRIBED
Hepadot Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Hepadot Injection may not be needed in these patients. Please consult your doctor.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1167-68.
Medscape. Protamine. view
Protamine. Lake Zurich, Illinois: Fresenius Kabi; 2016. view
Howland MA. Antidotes in Depth. In: Hoffman RS, Howland MA, Lewin NA, et al., editors. Goldfrank’s Toxicologic Emergencies. 10th ed. New York, New York: McGraw-Hill Education; 2015. . view
Protamine sulfate. Wrexham: Wockhardt UK Ltd.; 1991 . view
Drugs.com. Protamine Pregnancy and Breastfeeding Warnings. view
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