Macfuran Capsule

Composition Nitrofurantoin (100mg)
Rx Prescription Required
Pack strip of 30 capsules
Storage Store below 30°C
Chemical Class Nitrofurans derivatives
Action Class Urinary Antiseptic-Nitrofurantoin
Habbit Forming No
Manufacturer Macleods Pharmaceuticals Pvt Ltd
Manufacturer address Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai – 400059, INDIA.

Macfuran Capsule should be taken in the dose and duration as advised by the doctor. You may take it with food to avoid nausea, which is a common side effect. It is better to have this medicine at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like nausea, vomiting, and diarrhea. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. This medicine may turn your urine into dark yellow or brown color. But, this is normal and nothing to worry about.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any antibiotic.

Treatment of Bacterial infections of urinary tract

Take this medicine in the dose and duration as advised by your doctor. Macfuran Capsule is to be taken with food.

Macfuran Capsule is an antibiotic. It works by killing the bacteria in the urine that causes infection.

If you miss a dose of Macfuran Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Macfuran Capsule treats and prevents uncomplicated urinary tract infections.

Finish the prescribed course of the medicine, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Take it with food to avoid nausea, which is a common side effect.

It can turn your urine a dark yellow or brown colour. This is normal and nothing to worry about.

Do not take it for longer or more often than prescribed by your doctor.

Q. How long does Macfuran Capsule take to work on a UTI?

Macfuran Capsule starts acting quickly, but you will not start feeling better immediately after taking it. It may take a few days (2-3 days) before you see any improvement in your symptoms. If you do not start feeling better within 3 days of starting Macfuran Capsule or your condition worsens, contact your doctor. It is important to complete the full course of Macfuran Capsule as advised by your doctor, even if you start feeling better.

Q. What happens if you take Macfuran Capsule without food?

You should take Macfuran Capsule with your meal or straightaway after the meal. Taking with food helps in absorption of medicine so that it works better. If you take it without food, you are likely to get an upset stomach. The symptoms include nausea, vomiting, diarrhoea, and loss of appetite may also occur. Therefore, to avoid unpleasant side effects, take it exactly as prescribed by your doctor.

Q. Does Macfuran Capsule make your urine orange?

Macfuran Capsule may turn your urine brown or dark yellow in colour. However, you need not worry as this is usually temporary and completely harmless effect. It will disappear once you stop taking Macfuran Capsule. Consult your doctor if you are not sure or still have any concern, but do not stop taking Macfuran Capsule.

Q. Can Macfuran Capsule give you a yeast infection?

Yes, some people may get a fungal or yeast infection known as ‘thrush’ after taking Macfuran Capsule. This is because antibiotics kill the ‘good bacteria’ which help in preventing thrush. You should inform your doctor if you get vaginal itching or discharge after taking Macfuran Capsule or soon after stopping it.

Q. Is Macfuran Capsule a strong antibiotic?

Yes, Macfuran Capsule is a strong antibiotic (or broad spectrum antibiotic), which means that it is effective against a wide variety of urinary bacteria. It is important that Macfuran Capsule should be given to treat or prevent infections that are proven to be caused by susceptible bacteria. This is usually evaluated by a culture test which demonstrates a range of bacteria which cannot grow in the prence of an antibiotic. Macfuran Capsule has seen to be effective against UTI caused by Escherichia coli, Enteroccus faecalis, Klebsiella species, Enterobacter species, Staphylococcus species: (eg S. aureus, S. saprophyticus, S. epidermidis). Some strains of Enterobacter and Klebsiella are resistant to Macfuran Capsule.

In Treatment of Bacterial infections of urinary tract

Macfuran Capsule works by stopping the growth of the bacteria in the urine that cause urinary tract infections. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Diarrhea

Vomiting

Nausea

Alcohol:UNSAFE

Consuming alcohol while taking Macfuran Capsule may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy:SAFE IF PRESCRIBED

Macfuran Capsule is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:CAUTION

Macfuran Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving:UNSAFE

Macfuran Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CAUTION

Macfuran Capsule should be used with caution in patients with kidney disease. Dose adjustment of Macfuran Capsule may be needed. Please consult your doctor.Use of Macfuran Capsule is not recommended in patients with severe kidney disease, who are unable to pass urine or have high creatinine levels.

Liver:CAUTION

Macfuran Capsule should be used with caution in patients with liver disease. Dose adjustment of Macfuran Capsule may be needed. Please consult your doctor.Use of Macfuran Capsule is not recommended in patients with severe liver disease and active liver disease.

Petri WA Jr. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1474-75.

Chambers HF, Deck DH. Miscellaneous Antimicrobial Agents; Disingectants, Antiseptics, & Sterilants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 878.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 984-86.

Mayo Clinic. Nitrofurnatoin. view

Nitrofurantoin. North Norwich, New York: Norwich Pharmaceuticals, Inc.; 2008. Available form: view

U.S. Natioanl LIbrary of Medicine. Nitrofurantoin. view

Central Drugs Standard Control Organisation . view