MEGANite 10mg Tablet

MEGANite 10mg Tablet is used to treat erectile dysfunction (ED) in men and pulmonary arterial hypertension (PAH). It increases blood flow to the penis to help men get an erection. In PAH, it relaxes or widens the blood vessels inside the lungs, which reduces blood pressure in the lungs.

MEGANite 10mg Tablet may be taken on an empty stomach or with a meal. It should be strictly taken as advised by your doctor. The medicine when taken for ED will only help you to get an erection if you are sexually stimulated. You should take it about one hour before you plan to have sex. The amount of time it takes to work varies from person to person, but it normally takes between 30 minutes and one hour. Only take it if you need it and it has been prescribed to you by a doctor.

The most common side effects of this medicine are flushing, headache, blurred vision, muscle pain, stomach upset, nausea, back pain, and respiratory tract infection. Talk to your doctor if the side effects bother you or will not go away.

MEGANite 10mg Tablet can be dangerous to take it along with medicines called nitrates (often given for chest pain). Do not take this medicine if you have severe heart or liver problems, if you have recently had a stroke or heart attack or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems before taking it. You should not drive if this medicine makes you feel dizzy. Avoid drinking alcohol while taking this medicine as it can lead to side effects.

Treatment of Erectile dysfunction

Treatment of Pulmonary arterial hypertension (PAH)

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. MEGANite 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

MEGANite 10mg Tablet is a phosphodiesterase (PDE-5) inhibitor. It works in erectile dysfunction by increasing blood flow to the penis by relaxing the muscles in penile blood vessels. MEGANite 10mg Tablet also relaxes or widens the blood vessels inside the lungs. When the blood vessels relax and widen, it’s easier for the heart to pump blood through the lungs, which reduces blood pressure in the lungs.

Q: What if you forget to take MEGANite Tablet?
A: If you miss a dose of MEGANite 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

It is best to take it an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity.

Do not take it more than once a day.

Do not use MEGANite 10mg Tablet if you have recently taken nitrates (medicines used in angina or chest pain).

It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.

Avoid drinking alcohol as it can reduce your ability to get an erection and can make dizziness worse.

Seek medical attention if the erection persists for more than 4 hours after sexual intercourse.

Do not use MEGANite 10mg Tablet if you have recently taken nitrates (medicines used in angina or chest pain), if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.

Q. Can the use of MEGANite 10mg Tablet affect fertility?

No, using MEGANite 10mg Tablet does not affect fertility. It works by relaxing the muscles of penile blood vessels and has no effect on fertility.

Q. Do I need to avoid alcohol while taking MEGANite 10mg Tablet?

Alcohol in small amounts may not cause any discomfort to you. However, drinking too much alcohol (5 units or greater) can increase your chances of getting a headache or feeling dizzy, increased heart rate or low blood pressure.

Q. Does MEGANite 10mg Tablet delay ejaculation?

No, MEGANite 10mg Tablet is not known to affect ejaculation. It is used for the treatment of erectile dysfunction.

Q. What are the symptoms that should prompt me to discontinue MEGANite 10mg Tablet?

You should immediately consult your doctor if you experience sudden vision loss in one or both eyes, sudden decrease in hearing or hearing loss, ringing in ears and dizziness. Also, contact your doctor if you experience prolonged erections greater than 4 hours and painful erections greater than 6 hours in duration.

In Treatment of Erectile dysfunction

MEGANite 10mg Tablet belongs to a group of medicines called PDE5 inhibitors. It works by relaxing the blood vessels in your penis. This allows blood to flow into the penis and produce an erection when sexually aroused. This medicine will only help get an erection if you are sexually stimulated. It is very effective but needs to be taken at least 30 minutes before sexual activity. Do not take this medicine if you also take medicines called nitrates (often given for chest pain).

Back pain

Nausea

Flushing (sense of warmth in the face, ears, neck and trunk)

Headache

Blurred vision

Muscle pain

Upset stomach

Respiratory tract infection

Alcohol:UNSAFE

It is unsafe to consume alcohol with MEGANite 10mg Tablet.

Pregnancy:SAFE IF PRESCRIBED

MEGANite 10mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of MEGANite 10mg Tablet during breastfeeding is not available. Please consult your doctor.MEGANite 10mg Tablet is not indicated for use in women.

Driving:UNSAFE

MEGANite 10mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CAUTION

MEGANite 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of MEGANite 10mg Tablet may be needed. Please consult your doctor.

Liver:CAUTION

MEGANite 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of MEGANite 10mg Tablet may be needed. Please consult your doctor.Use of MEGANite 10mg Tablet is not recommended in patients with severe liver disease.

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 752-53.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 197.
Tadalafil. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2008 [revised 23 March 2017]. [Accessed 22 Jan. 2019] (online) Available from: View
Tadalafil. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2002 [revised 23 Mar. 2017]. [Accessed 04 Apr. 2019] (online) Available from: View
Tadalafil. Indianapolis, Indiana: Eli Lilly and Company; 2007. [Accessed 04 Apr. 2019] (online) Available from: View
Central Drugs Standard Control Organisation. Tadalafil. [Accessed 07 Aug. 2023]. (online) Available from: View
Tadalafil [Product Monograph]. Toronto, Ontario: © Eli Lilly Canada Inc.; 2020. [Accessed 07 Aug. 2023]. (online) Available from: View
Tadalafil [Prescribing Information]. Basking Ridge, NJ: Torrent Pharmaceuticals Limited; 2022. [Accessed 07 Aug. 2023]. (online) Available from: View