Megatas Plus 25 Combikit

Megatas Plus 25 Combikit is advised to be taken in the dose and duration as prescribed by your doctor. It may be taken with or without food, preferably at the same time each day. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine.

Some of the common side effects of this medicine are hypertension (high blood pressure), nasopharyngitis (inflammation of the throat and nasal passages), urinary tract infection, and headache. If any of the side effects bother you or persist, consult the doctor without delay.

Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. People with liver or kidney disease must be cautious while receiving the prescription and they must receive regular follow-ups as per the doctor’s advice.

Overactive bladder (OAB) symptoms

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Megatas Plus 25 Combikit may be taken with or without food, but it is better to take it at a fixed time.

Megatas Plus 25 Combikit is a combination of two medicines: Mirabegron and Solifenacin. Mirabegron is a beta 3-receptor agonist. It works by activating the receptor in the bladder, causing the bladder muscles to relax. Solifenacin is an antimuscarinic. It also works by relaxing muscles of the urinary bladder. In this way, it works to prevent frequent, urgent, or uncontrolled urge of urination.

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Megatas Plus 25 Combikit helps you to have better control over your urination.

It may raise your blood pressure. Monitor your blood pressure regularly.

Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.

Avoid caffeine (tea, coffee, cola, etc.) as it is a natural diuretic (increased urine production) and will make your symptoms worse.

Avoid drinking too much water before going to bed as it will increase your urge to go to the toilet and thus disturb your sleep.

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In Overactive bladder (OAB) symptoms

Megatas Plus 25 Combikit helps to treat uncontrollable contractions (spasms) of the bladder muscles that cause frequent urination, urgent need to urinate, and inability to control passing of urine. It also relieves painful, or frequent urination and reduces urgency to urinate that may occur with some infections of the urinary tract. This way it helps manage the overactive bladder symptoms efficiently.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Blurred vision

Increased heart rate

Constipation

Dryness in mouth

Headache

Urinary tract infection

Nasopharyngitis (inflammation of the throat and nasal passages)

High blood pressure

Alcohol:CAUTION

Caution is advised when consuming alcohol with Megatas Plus 25 Combikit. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Information regarding the use of Megatas Plus 25 Combikit during pregnancy is not available. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of Megatas Plus 25 Combikit during breastfeeding is not available. Please consult your doctor.

Driving:CONSULT YOUR DOCTOR

It is not known whether Megatas Plus 25 Combikit alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney:CONSULT YOUR DOCTOR

There is limited information available on the use of Megatas Plus 25 Combikit in patients with kidney disease. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Megatas Plus 25 Combikit in patients with liver disease. Please consult your doctor.

Brown JH, Brandl K, Wess J. Muscarinic Receptor Agonists and Antagonists. In: Brunton LL, Hilal-Dandan R, Knollmann BC . Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 149-161.

Pappano AJ. Cholinoceptor-Blocking Drugs. In: Katzung BG, Masters SB, Trevor AJ . Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 113-126.