Composition Tobramycin (0.3% w/w)
Rx Prescription Required
Pack tube of 5 gm Ophthalmic Gel
Storage
Chemical Class Aminoglycosides
Action Class Aminoglycosides
Habbit Forming No
Manufacturer Senses Pharmaceuticals Ltd
Manufacturer address New No:4, (Old No:15/4), Hemanth Plaza, 80 Feet Main Road, 2nd Stage, Padmanabhanagar, Benguluru – 560070.

Obrin Ophthalmic Gel
Obrin Ophthalmic Gel is an antibiotic medicine that is used to treat bacterial infections of the eye (e.g., conjunctivitis) and the eyelids (e.g., blepharitis). It may also help to prevent an infection after an eye injury or surgery.
Basic Info
Description
Obrin Ophthalmic Gel stops the growth of bacteria and thereby helps to cure the underlying infection. Follow your doctor’s instructions precisely for administering this medicine. Wait for at least 5 minutes before applying any other eye medication. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Obrin Ophthalmic Gel will not work for eye infections that are not caused by bacteria (e.g., viral) and therefore, should only be used if prescribed by your doctor. Unnecessary use of any antibiotic can lead to a decrease in its effectiveness in the future.
Common side effects seen with this medicine include temporary eye irritation, burning sensation, itching, and redness after administration. Consult your doctor if these side effects persist or if your condition worsens. It may cause some short-term blurring of vision when first used. Therefore, do not drive immediately after administering this medicine. Contact lenses should not be worn while you are using this medicine or while you have an active eye infection.
Uses
Treatment of Bacterial eye infections
How To Use
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the tube close to the eye without touching it. Gently squeeze the tube and place the medicine inside the lower eyelid.
MOA
Obrin Ophthalmic Gel is an antibiotic. It stops bacterial growth in the eye by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This treats your eye infection.
What If
If you miss a dose of Obrin Ophthalmic Gel, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Your doctor has prescribed Obrin Ophthalmic Gel to treat bacterial infections of the eye.
Do not skip any doses and finish the full course of treatment even if you feel better.
Obrin Ophthalmic Gel may cause damage to cornea on long-term use.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
Make sure to use it within 4 weeks of opening the bottle.
Can I stop taking Obrin Ophthalmic Gel when I feel better?
Do not skip any doses and finish the full course of treatment even if you feel better.
Obrin Ophthalmic Gel may cause damage to cornea on long-term use.
Apply pressure on the corner of the eye (close to the nose) for about 1 minute immediately after instilling the drop.
Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
Stinging sensation may occur for 1-2 mins. Notify your doctor if it persists for longer.
Make sure to use it within 4 weeks of opening the bottle.
Faqs
Q. Does Obrin Ophthalmic Gel have a steroid in it?
No, Obrin Ophthalmic Gel alone does not have steroids in it. It is an antibiotic, which means that it is effective against bacterial infections. It is not effective against viral or fungal infections and hence should not be used in these kinds of infections. Obrin Ophthalmic Gel may be combined with steroids such as dexamethasone.
Q. What bacteria does Obrin Ophthalmic Gel kill?
Obrin Ophthalmic Gel is effective against a wide range of bacteria. Obrin Ophthalmic Gel must be used only against susceptible bacteria. A whole gamut of bacteria that can be killed by Obrin Ophthalmic Gel includes S. Aureus and S. epidermidis, some species of Streptococci, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenza, and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus, and some Neisseria species. Your doctor will evaluate whether this medicine is suitable for your condition.
Q. How long should you use Obrin Ophthalmic Gel?
The doctor will decide the duration of treatment which will depend on the severity of infection. For instance, if you have mild to moderate eye infection, your doctor will advise 1-2 eye drops, 4 times a day, usually. In severe infections, you may be prescribed 2 drops every hour. Do not use more or less of it or use it more often than prescribed by your doctor. You should use it exactly as prescribed by your doctor.
Q. How should Obrin Ophthalmic Gel be used?
You should wash your hands before using the eye drops. Avoid touching the dropper tip against your eye or anywhere else. Tilt your head slightly and instill one drop. Close your eyes for 2 or 3 minutes with your head tipped down, avoid blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct. If you use more than one drop, wait about 5 minutes between the drops. Wait at least 10 minutes before using any other eye drops your doctor has prescribed.
Q. Is Obrin Ophthalmic Gel effective?
Obrin Ophthalmic Gel is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Obrin Ophthalmic Gel too early, the symptoms may return or worsen.
Q. What if I don’t get better after using Obrin Ophthalmic Gel?
Inform your doctor if you don’t feel better after finishing the full course of treatment. Also, inform the doctor if your symptoms are getting worse while using this medicine.
Q. Can I stop taking Obrin Ophthalmic Gel when I feel better?
No, do not stop taking Obrin Ophthalmic Gel without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
Benifits
In Treatment of Bacterial eye infections
Obrin Ophthalmic Gel is an antibiotic medicine. It works by stopping the growth of the bacteria that is causing the infection. It helps relieve symptoms such as pain, redness, itching, or soreness caused due to eye infections. The dose and duration of treatment will be decided by your doctor based on your condition. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Eye itching
Eye redness
Burning sensation
Eye irritation
Safety Profile
Alcohol:
No interaction found/established
Pregnancy:CONSULT YOUR DOCTOR
Obrin Ophthalmic Gel is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Obrin Ophthalmic Gel is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:SAFE
Obrin Ophthalmic Gel does not usually affect your ability to drive.
Kidney:
No interaction found/established
Liver:
No interaction found/established
Refferences
MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmanโs: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1516.
Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 812.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1371-72.
Drugs.com. Tobramycin Ophthalmic Solution. view
Drugs.com. Tobramycin Pregnancy and Breastfeeding Warnings. view
Central Drugs Standard Control Organisation . view

