Orinase Oxy AD 0.05% Nasal Spray

Orinase Oxy AD 0.05% Nasal Spray is a medicine used to treat nasal congestion (blocked nose) caused by the common cold or flu, hay fever and other allergies. It narrows the blood vessels in your nose to relieve nasal congestion and blockage.

Orinase Oxy AD 0.05% Nasal Spray should be used as you have been advised by your doctor. Normally you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat the same for the other nostril. It provides relief very quickly and can last for several hours. It provides only temporary relief but do not use it more often or for longer than recommended. If you use this medicine too often or for too long, it may worsen your symptoms rather than improve them.

The most common side effects are nose irritation and dryness of the mouth or throat. These are usually mild but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

It is generally a safe medicine but, before taking it, talk to your doctor about any health problems you have such as heart problems or high blood pressure (hypertension) or overactive thyroid gland or glaucoma (increased pressure in the eye), or prostate enlargement. Let your doctor know about any other medicines you are taking to make sure you are safe. Ask your doctor for advice before using this medicine if you are pregnant or breastfeeding.

Nasal congestion (blocked nose)

Conjunctivitis

Uveitis

Pupil dilation

Eye Irritation

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

Orinase Oxy AD 0.05% Nasal Spray is a nasal decongestant. It works by narrowing the small blood vessels in the inner surface of the nose. This provides temporary relief from congestion or stuffiness in the nose.

Q: What if you forget to take this medicine?
A:

It works right away and each dose provides relief for up to 12 hours.

The right way to use the nasal spray:Shake the bottle before using the medicine.Clean your nose thoroughly before using the medicine.Insert the bottle tip into one nostril and close the other nostril.Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.Breathe out gently through your mouth and repeat the same process for the other nostril.

Shake the bottle before using the medicine.

Clean your nose thoroughly before using the medicine.

Insert the bottle tip into one nostril and close the other nostril.

Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose.

Breathe out gently through your mouth and repeat the same process for the other nostril.

Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.

Do not share the bottle with anyone else so that you do not spread germs.

Orinase Oxy AD 0.05% Nasal Spray can make nasal congestion worse if used for more than 3 or 4 days in a row (called rebound congestion).

Q. Is Orinase Oxy AD 0.05% Nasal Spray addictive?

Treatment with Orinase Oxy AD 0.05% Nasal Spray does not cause mental addiction. However, patients may get physically addicted such that they may feel an urge to use Orinase Oxy AD 0.05% Nasal Spray. Hence, it should only be used at prescribed doses for the prescribed duration as advised by your doctor.

Q. Is Orinase Oxy AD 0.05% Nasal Spray a steroid/ antihistamine?

No, Orinase Oxy AD 0.05% Nasal Spray is not a steroid or an antihistamine. It belongs to a class of medications called adrenergic medicines that are used as nasal decongestants (to relieve congestion of the nose).

Q. Is Orinase Oxy AD 0.05% Nasal Spray safe?

Orinase Oxy AD 0.05% Nasal Spray is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

Q. Does Orinase Oxy AD 0.05% Nasal Spray cause cataract/keep you awake/ raise blood pressure/insomnia/drowsiness?

There are no such reports which suggest occurrence of side effects such as cataract, insomnia (inability to sleep) or drowsiness during treatment with Orinase Oxy AD 0.05% Nasal Spray. However, Orinase Oxy AD 0.05% Nasal Spray can raise blood pressure when taken with medicines that are used to treat depression, like selegiline and moclobemide. It can also decrease the effect of medicines used to treat blood pressure. Hence, patients should consult doctors regarding the possible side effects and drug interactions.

Q. Can I take Orinase Oxy AD 0.05% Nasal Spray with Benadryl (diphenhydramine)/ phenylephrine/ pseudoephedrine?

Orinase Oxy AD 0.05% Nasal Spray should not be taken simultaneously with Benadryl (diphenhydramine)/phenylephrine/pseudoephedrine. Consult your doctor before using any other medicine with Orinase Oxy AD 0.05% Nasal Spray.

Dryness

Dry throat

Irritation

Sneezing

Alcohol:

No interaction found/established

Pregnancy:CONSULT YOUR DOCTOR

Orinase Oxy AD 0.05% Nasal Spray may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Orinase Oxy AD 0.05% Nasal Spray is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.To reduce the amount of Orinase Oxy AD 0.05% Nasal Spray that reaches the breastmilk, remove the excess solution with an absorbent tissue.

Driving:

No interaction found/established

Kidney:

No interaction found/established

Liver:

No interaction found/established

Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 140.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1041-42.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from: View