Phenytoin Sodium 100mg Injection

Phenytoin Sodium 100mg Injection is given under the supervision of a healthcare professional and should not be self-administered. It is advisable to take it at the same time each day as this helps to maintain a constant level of medicine in the body. If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better as stopping the medication without talking to your doctor may cause non-stop seizures (called status epilepticus), which can be life-threatening.

The most common side effects of this medicine include skin rashes, headache, feeling or being sick, difficulty sleeping, dizziness, and feeling sleepy or drowsy. Additionally, you may notice some injection site reactions like redness or swelling. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

Treatment and prevention of Epilepsy/Seizures

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Phenytoin Sodium 100mg Injection is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

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Take your medication regularly as directed by your doctor as missing doses can trigger seizures.

Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.

Some healthy tips to prevent seizures:Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/laptop.Take your medication on time.

Practice yoga every day.

Get enough sleep at nighttime.

Limit the use of screen time such as mobile/laptop.

Take your medication on time.

It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.

It may increase blood sugar levels. Inform your doctor if you are taking any medicines to treat diabetes.

It may cause swollen gum (gum hypertrophy), hence take care of oral or dental hygiene.

Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Q. For how long does Phenytoin Sodium 100mg Injection stay in your system?

On an average, Phenytoin Sodium 100mg Injection may stay in your system for 5-6 days. This duration varies from person to person. In some cases, it may stay for about 9-10 days.

Q. Who should avoid taking Phenytoin Sodium 100mg Injection?

You should not take Phenytoin Sodium 100mg Injection if you have liver disease, especially if you have a history of developing a liver problem due to Phenytoin Sodium 100mg Injection. Also, patients taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Phenytoin Sodium 100mg Injection. Phenytoin Sodium 100mg Injection may reduce the effectiveness of Delavirdine on HIV and the virus may also become resistant to Delavirdine. It is advised that you inform your doctor if you have any existing heart disorder before you receive Phenytoin Sodium 100mg Injection.

Q. Can I take Phenytoin Sodium 100mg Injection with ibuprofen?

Phenytoin Sodium 100mg Injection can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

Q. What are the effects of Phenytoin Sodium 100mg Injection on children?

The most common side effects related to Phenytoin Sodium 100mg Injection in children are jerky movements of the eyes (nystagmus) and overgrowth of the gums. In some children, Phenytoin Sodium 100mg Injection causes problems with thinking or behavior, mood change, slow or clumsy movements, or a loss of energy. Other side effects from high doses include unsteadiness in the feet and hands, sleepiness, and vomiting. These may be avoidable if the dose is increased slowly. These side effects quickly disappear when the dose is reduced.

Q. Does Phenytoin Sodium 100mg Injection cause weight gain?

Phenytoin Sodium 100mg Injection has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Phenytoin Sodium 100mg Injection. Please consult your doctor if you experience weight gain after taking Phenytoin Sodium 100mg Injection.

Q. Does Phenytoin Sodium 100mg Injection make you sleepy?

Phenytoin Sodium 100mg Injection can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Phenytoin Sodium 100mg Injection, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.

Q. Does Phenytoin Sodium 100mg Injection affect birth control?

Phenytoin Sodium 100mg Injection does affect birth control. Phenytoin Sodium 100mg Injection can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.

In Treatment and prevention of Epilepsy/Seizures

Phenytoin Sodium 100mg Injection is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Altered walking

Tremor

Constipation

Nervousness

Confusion

Vertigo

Slurred speech

Nausea

Vomiting

Dizziness

Headache

Rash

Alcohol:UNSAFE

It is unsafe to consume alcohol with Phenytoin Sodium 100mg Injection.

Pregnancy:CONSULT YOUR DOCTOR

Phenytoin Sodium 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

Phenytoin Sodium 100mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.Please consult your doctor.

Driving:UNSAFE

Phenytoin Sodium 100mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:CAUTION

Phenytoin Sodium 100mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Phenytoin Sodium 100mg Injection may be needed. Please consult your doctor.

Liver:CAUTION

Phenytoin Sodium 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Phenytoin Sodium 100mg Injection may be needed. Please consult your doctor.

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Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 403-405.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1111-116.

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