Composition Metformin (500mg) + Vildagliptin (50mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30ยฐC
Chemical Class
Action Class
Habbit Forming No
Manufacturer USV Ltd
Manufacturer address Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai – 400 088. , India.

Jalra-M 50mg/500mg Tablet
Jalra-M 50mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.
Basic Info
Description
Jalra-M 50mg/500mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.
You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it.
This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.
Uses
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How To Use
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MOA
Jalra-M 50mg/500mg Tablet is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body’s sensitivity to insulin.
What If
If you miss a dose of Jalra-M 50mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
You have been prescribed Metformin to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metformin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Metformin may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.
Faqs
Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the bodyโs response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.
Q. When should I take Vildagliptin?
You can take Vildagliptin tablets before, with or after meals. If you have been prescribed to take this medicine once daily, then take it in the morning. In case you have to take it twice daily, then you should prefer taking the first dose in the morning and the second dose in the evening.
Q. Does Vildagliptin cause hypoglycemia?
Yes, Vildagliptin may cause hypoglycemia (low blood sugar), but the chances are lesser as compared to other antidiabetic drugs. Evidence suggests that treatment with Vildagliptin has been shown to cause hypoglycemia in very rare cases. The risk is low even in those who are prone to hypoglycemia like elderly people or people being treated with insulin. However, the chance of hypoglycemia increases if Vildagliptin is taken along with other antidiabetic drugs.
Q. Does Vildagliptin cause weight gain?
No, Vildagliptin does not cause weight gain. Moreover, medicines, such as Vildagliptin, are generally supposed to decrease weight since they act by increasing satiety (feeling of fullness) and delaying emptying of the stomach. This further decreases hunger, restricting the patient from eating more than required.
Q. Is Vildagliptin the same as sitagliptin?
No, Vildagliptin is not the same as Sitagliptin, but both drugs belong to the same class. Additionally, these two drugs have a similar mechanism of decreasing blood glucose levels.
Benifits
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Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if youโre worried about them
Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
Sweating
Dizziness
Constipation
Cough
Common cold
Headache
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Jalra-M 50mg/500mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Jalra-M 50mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Jalra-M 50mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving:CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney:CAUTION
Jalra-M 50mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Jalra-M 50mg/500mg Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Jalra-M 50mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Jalra-M 50mg/500mg Tablet may be needed. Please consult your doctor.Regular monitoring of liver function tests is recommended if you are taking this medicine. Use of this medicine is preferably not advised in patients with liver disease.
Refferences
Vildagliptin/metformin hydrochloride. Nuremberg, Germany: Novartis Pharma GmbH; 2018. view
Vildagliptin/metformin hydrochloride. Macquarie Park, New South Wales: Novartis Pharmaceuticals Australia Pty Limited; 2010 . view
Vildagliptin. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2007 view
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. view

