Ondem 4 Tablet

Composition Ondansetron (4mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30°C
Chemical Class Carbazole Derivative
Action Class Serotonin antagonists (5-HT3 antagonists)
Habbit Forming No
Manufacturer Alkem Laboratories Ltd
Manufacturer address Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai – 400 013.

Ondem 4 Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.

This medicine does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea, or constipation and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them. 

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Treatment of Nausea
Treatment of Vomiting

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ondem 4 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Ondem 4 Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

If you miss a dose of Ondem 4 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

You have been prescribed Ondem 4 Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.

It is fast-acting and starts working within 30 minutes.

If you vomit within one hour of taking a dose, take another dose.

Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Q. How quickly does Ondem 4 Tablet work?

Ondem 4 Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Ondem 4 Tablet?

The most common side effects of Ondem 4 Tablet are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Q. When should you take Ondem 4 Tablet?

Ondem 4 Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Ondem 4 Tablet is taken before the start of your surgery, chemotherapy or radiation treatment.

Q. Is Ondem 4 Tablet a steroid?

No, Ondem 4 Tablet is an antiemetic and not a steroid. Ondem 4 Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Q. Does Ondem 4 Tablet work for seasickness?

No, Ondem 4 Tablet does not work for seasickness. This is because Ondem 4 Tablet has very little effect on the nausea associated with motion sickness.

In Treatment of Nausea

Ondem 4 Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Headache

Fatigue

Diarrhea

Constipation

Alcohol:SAFE

Consuming alcohol with Ondem 4 Tablet does not cause any harmful side effects.

Pregnancy:SAFE IF PRESCRIBED

Ondem 4 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:SAFE IF PRESCRIBED

Ondem 4 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:SAFE

Ondem 4 Tablet does not usually affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Ondem 4 Tablet is safe to use in patients with kidney disease. No dose adjustment of Ondem 4 Tablet is recommended.However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Ondem 4 Tablet in patients with liver disease. Please consult your doctor.

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.

Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285

Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 . view

Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Ondansetron. . view

Central Drugs Standard Control Organisation . view