Composition Thyroxine (12.5mcg)
Rx Prescription Required
Pack bottle of 100 tablets
Storage Store below 30°C
Chemical Class Iodinated amino acid derivative
Action Class Thyroid hormones
Habbit Forming No
Manufacturer Macleods Pharmaceuticals Pvt Ltd
Manufacturer address Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai – 400059, INDIA.

Thyrox 12.5 Tablet
Thyrox 12.5 Tablet is a medicine used to treat an underactive thyroid gland (hypothyroidism). It replaces the hormone which is not being produced by your thyroid gland in sufficient quantity and helps regulate your body’s energy and metabolism.
Basic Info
Description
Before you start taking Thyrox 12.5 Tablet, your doctor will do a blood test to see what dose you need. Once you start taking the medicine, you will have regular blood tests to see how well it is working, and the dose may be adjusted from time to time. It is best taken on an empty stomach before your first meal of the day. You should take this medicine regularly to get the maximum benefit. It may take several weeks before your symptoms start to improve. You may need to take it for the rest of your life. If you stop taking it, your symptoms are likely to come back.
The most common side effects of this medicine are caused by taking a higher dose than you need. Possible side effects include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, nervousness, or restlessness. Most side effects will disappear once you are on the right dose. Call your doctor straight away if you have a very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits.
Thyrox 12.5 Tablet may cause weight loss but should not be prescribed or taken to treat obesity. If you become pregnant while taking this medicine, inform your doctor right away as the dose may have to be increased/readjusted. Many other drugs affect the way this medicine works. Ask your doctor for advice if you are taking any other medications.
Uses
Treatment of Hypothyroidism
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thyrox 12.5 Tablet is to be taken empty stomach.
MOA
Thyrox 12.5 Tablet is a synthetic version of a hormone produced by the thyroid gland. It works by replacing the thyroid hormones that your thyroid gland cannot produce in a sufficient quantity, and relieves the symptoms of hypothyroidism (tiredness, weight gain, and depression).
What If
If you miss a dose of Thyrox 12.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Thyrox 12.5 Tablet should be taken on an empty stomach (ideally, first thing in the morning). No food, milk, or tea should be taken 1 hour before and 2 hours after taking this medicine.
It may take 6 to 8 weeks to get the full effect.
For most people, Thyrox 12.5 Tablet can be a lifelong medication. Do not discontinue it without discussing your doctor.
Inform your doctor if you have diarrhea, nervousness, irritability, sleep disturbances, shaking hands, or chest pain. Your doctor may adjust your dose.
Leave a gap of at least 4 hours before taking any antacids, calcium or iron supplements, and multivitamins, as these may interfere with the effect of the medicine.
Get your hormone levels checked regularly and inform your doctor if you notice a significant change in your body weight. The dose may need to be adjusted.
Inform your doctor before changing the brand of Thyrox 12.5 Tablet as all brands may not have the same effect.
Faqs
Q. What should I do if I accidentally take more than the dose required?
An overdose of this medicine may cause nervousness, anxiety, rapid heartbeat, hand tremors, excessive sweating, weight loss, and sleep problems. You should immediately consult your doctor in case of an overdose.
Q. How long do I need to take Thyrox 12.5 Tablet?
You should take Thyrox 12.5 Tablet as long as your doctor has recommended. Usually, it is prescribed for the long term and you may have to take it lifelong. Do not stop taking the medicine, as your symptoms of low levels of thyroid hormone may reoccur.
Q. How should Thyrox 12.5 Tablet be taken?
Take Thyrox 12.5 Tablet exactly as advised by your doctor. Thyrox 12.5 Tablet should be taken orally preferably before breakfast or as a first meal of the day. It should be swallowed whole with plenty of water.
Q. Being a diabetic what should I be aware of while taking Thyrox 12.5 Tablet?
Thyrox 12.5 Tablet may raise blood sugar levels and may affect the working of other anti-diabetic medicines which you might be taking. Hence, dose adjustment may be required. Consult your doctor who will help you with dose management.
Q. What does thyroxine do? Why is it important?
Thyroxine hormone controls how much energy your body uses. It plays an important role in regulating your body weight, muscle strength, body temperature, and even your mood. Along with that, it is important for your digestion, heart muscles, brain development, and bone health.
Q. Does Thyrox 12.5 Tablet affect contraception?
Oral birth control pills, which contain both estrogen and progesterone may reduce the amount of Thyrox 12.5 Tablet in your body and therefore the dose of Thyrox 12.5 Tablet may have to be increased.
Benifits
In Treatment of Hypothyroidism
Thyrox 12.5 Tablet is a synthetic version of thyroxine, a hormone that is naturally produced in your body. When your body does not produce enough thyroxine, you get hypothyroidism. Some symptoms of hypothyroidism include tiredness, weight gain, and muscle aches. This medicine raises your hormone level to the right amount and helps you get rid of these symptoms. For most people, this is a lifelong medication and should not be discontinued without talking to your doctor.It may take a while for this medicine to work properly. Your doctor may get regular blood tests done to determine the effectiveness of this medicine and to make sure that you are on the right dose.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Restlessness
Nervousness
Weight loss
Flushing (sense of warmth in the face, ears, neck and trunk)
Diarrhea
Anxiety
Vomiting
Palpitations
Safety Profile
Alcohol:SAFE
Consuming alcohol with Thyrox 12.5 Tablet does not cause any harmful side effects.
Pregnancy:SAFE IF PRESCRIBED
Thyrox 12.5 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding:SAFE IF PRESCRIBED
Thyrox 12.5 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:SAFE
Thyrox 12.5 Tablet does not usually affect your ability to drive.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Thyrox 12.5 Tablet in patients with kidney disease. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Thyrox 12.5 Tablet in patients with liver disease. Please consult your doctor.
Refferences
Brent GA, Koenig RJ. Thyroid and Anti-Thyroid Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1142-43.
Dong BJ, Greenspan FS. Thyroid & Antithyroid Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 674-75.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 796-98.
Levothyroxine. Barnstaple, UK: Actavis; 2018. view
Levothyroxine sodium. East Sussex, UK: Custom Pharmaceuticals Ltd.; 2018. view
Levothyroxine. Bohemia, New York: Jerome Stevens Pharmaceuticals, Inc. view

