Topivar 25mg Tablet
Topivar 25mg Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Topivar 25mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Topivar 25mg Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Topivar 25mg Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).
Topivar 25mg Tablet may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause an increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.
Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter. You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.
03Uses
Epilepsy
Mania
Epilepsy/Seizures
Migraine
Lennox–Gastaut syndrome
Trigeminal neuralgia
Seizures
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topivar 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Topivar 25mg Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.
06What If You Miss A Dose?
Q: What if you forget to take Topivar Tablet?
A: If you miss a dose of Topivar 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Epilepsy/Seizures
Topivar 25mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.
08Side Effects
Abdominal pain
Diarrhea
Dizziness
Fatigue
Fever
Loss of appetite
Memory impairment
Nausea
Nervousness
Numbness
Psychomotor impairment
Sleepiness
Speech disorder
Taste change
Upper respiratory tract infection
Visual impairment
Weight loss
09Safety Information
Alcohol:UNSAFE
It is unsafe to consume alcohol with Topivar 25mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Topivar 25mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Topivar 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Topivar 25mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CAUTION
Topivar 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Topivar 25mg Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Topivar 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Topivar 25mg Tablet may be needed. Please consult your doctor.
10Drug Tips
Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:Practice yoga every day.Get enough sleep at nighttime.Limit the use of screen time such as mobile/laptop.Take your medication on time.
Practice yoga every day.
Get enough sleep at nighttime.
Limit the use of screen time such as mobile/laptop.
Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topivar 25mg Tablet. This can reduce the risk of kidney stones.
Monitor your weight during treatment with this medicine as it can cause weight gain.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
References
Sources and references
Stahl SM, editor. Topiramate. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 669-73.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 601.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 12.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1380-82.
Topiramate. High Wycombe, Bucks: Janssen-Cilag Ltd.; 1995 [revised 13 Dec. 2017]. [Accessed 22 Jan. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Topiramate. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from: View
Topiramate. Gurabo, Puerto Rico: Janssen Ortho; 2012. [Accessed 18 Mar. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from: View
Topiramate [Prescribing Information]. 2012. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2009. [Accessed 20 Feb. 2024] (online) Available from: View
