Composition Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg)
Rx Prescription Required
Pack strip of 15 tablet sr
Storage Store below 30°C
Chemical Class
Action Class
Habbit Forming No
Manufacturer Micro Labs Ltd
Manufacturer address 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Glimepiride (2mg) + Metformin (500mg) + Pioglitazone (15mg)
PRIMARY PRODUCT
VIEW AVAILABLE SUBSTITUTES
Tripride 2 Tablet SR
Tripride 2 Tablet SR is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.
Basic Info
Description
Tripride 2 Tablet SR should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).
Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.
Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.
Uses
Information not available at the moment. Please check back later.
How To Use
Information not available at the moment. Please check back later.
MOA
Tripride 2 Tablet SR is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
What If
Information not available at the moment. Please check back later.
Drug Tips
Glimepiride helps decrease high blood sugar level and avoid long-term complications of diabetes.
Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
Monitor your blood sugar level regularly while you are taking this medicine.
Be careful while driving or operating machinery until you know how Glimepiride affects you.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Faqs
Q. Does Glimepiride make you sleepy?
Glimepiride itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Q. Is Glimepiride safe for kidneys?
Glimepiride does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Glimepiride is principally eliminated by the kidneys.
Q. Does Glimepiride cause memory loss?
No, it is not known that Glimepiride causes memory loss. However, the use of Glimepiride may cause low blood sugar which may cause problems with concentration and reduced alertness.
Q. Who should not take Glimepiride?
Glimepiride should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Glimepiride.
Q. How long does it take for Glimepiride to start working?
Glimepiride takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
Q. How long do I need to take Glimepiride? Can I stop the medication?
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Glimepiride only controls the sugar levels but does not cure it. Do not stop taking Glimepiride without talking to your doctor. If you stop taking Glimepiride suddenly your diabetes may get worse.
Q. How and when to take Glimepiride?
Glimepiride is advised to be taken in the dose and duration suggested by your doctor. Generally, a single daily dose of Glimepiride is sufficient to control blood sugar levels. The dose should be taken whole with water shortly before or during breakfast. However, if you skip breakfast then the medicine should be taken shortly before or during your first main meal.
Q. What can happen if I take more than the recommended dose of Glimepiride?
Glimepiride should be taken strictly as advised by the doctor. Overdose of Glimepiride may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.
Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.
Q. Can Pioglitazone cause weight gain?
Pioglitazone commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.
Q. Can Pioglitazone cause heart failure?
Pioglitazone can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Pioglitazone is used with insulin.
Q. Can you take Pioglitazone and metformin together?
Yes, Pioglitazone can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.
Q. What time of day should you take Pioglitazone?
It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Pioglitazone exactly as prescribed by your doctor.
Q. How long do I need to take Pioglitazone? Can I stop the medicine for some time?
Continue taking Pioglitazone as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.
Q. Can Pioglitazone cause bladder cancer?
Pioglitazone may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Pioglitazone should not be used in patients with a prior history of bladder cancer or having bladder cancer.
Q. Does Pioglitazone affect liver?
Yes, Pioglitazone may cause an increase in liver enzymes, and treatment with Pioglitazone should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Pioglitazone should not be prescribed to patients with liver disease.
Q. What kind of medicine is Pioglitazone? Is it like metformin?
Pioglitazone belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.
Benifits
Information not available at the moment. Please check back later.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Bone fracture
Numbness
Respiratory tract infection
Blurred vision
Weight gain
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Tripride 2 Tablet SR.
Pregnancy:CONSULT YOUR DOCTOR
Tripride 2 Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Tripride 2 Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Monitor the breastfed baby’s blood sugar during treatment with Tripride 2 Tablet SR
Driving:CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney:CAUTION
Tripride 2 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Tripride 2 Tablet SR may be needed. Please consult your doctor.Use of Tripride 2 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver:CAUTION
Tripride 2 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Tripride 2 Tablet SR may be needed. Please consult your doctor.Use of Tripride 2 Tablet SR is not recommended in patients with severe liver disease.
