Tyzine Plus 40mg/10mg Tablet
Tyzine Plus 40mg/10mg Tablet is a combination medicine used for the prevention of migraines. It works by regulating brain activity and improving blood flow, helping to reduce the frequency, severity, and intensity of migraine attacks.
Tyzine Plus 40mg/10mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Tyzine Plus 40mg/10mg Tablet is a combination medicine used for the prevention of migraines. It works by regulating brain activity and improving blood flow, helping to reduce the frequency, severity, and intensity of migraine attacks.
Tyzine Plus 40mg/10mg Tablet is a combination medicine used for the prevention of migraines. It works by regulating brain activity and improving blood flow, helping to reduce the frequency, severity, and intensity of migraine attacks.
Tyzine Plus 40mg/10mg Tablet can be taken with or without food. Take it regularly and at the same time each day for maximum benefits. The dose and how often you take it will depend on your condition and the severity of your symptoms. Your doctor will decide how much you need to improve your symptoms. Take it for as long as it is prescribed for you. Lifestyle modifications like avoiding stress, smoking, and processed food items may help this medicine work better.
Common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness, and cold extremities. The drug can hide the symptoms of the blood sugar level, hence monitor your blood sugar level regularly as well as your blood pressure while taking this medicine.
Before taking this medicine, let your doctor know if you have liver or kidney disease, depression, or if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works.
Individuals suffering from any breathing problems, including asthma or bronchitis, should inform the doctor before using Tyzine Plus 40mg/10mg Tablet. It can also cause weight gain in some people, so the person is advised to maintain a healthy diet plan to maintain their weight.
03Uses
Prevention of Migraine
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tyzine Plus 40mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Tyzine Plus 40mg/10mg Tablet is a combination of two medicines: propranolol and flunarizine. Propranolol is a beta blocker, and flunarizine is a calcium channel blocker. They work together by stabilizing the reactive nerve cells and increasing the threshold for migraine activation. Flunarizine also helps in inhibiting cortical spreading depression (CSD—electric waves that move across the brain and cause pain and inflammation).
06What If You Miss A Dose?
Q: What if you forget to take Tyzine Plus Tablet?
A: If you miss a dose of Tyzine Plus 40mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Prevention of Migraine
Tyzine Plus 40mg/10mg Tablet helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.
08Side Effects
Weight gain
Slow heart rate
Tiredness
Depression
Drowsiness
Cold extremities
09Safety Information
Alcohol:UNSAFE
It is unsafe to consume alcohol with Tyzine Plus 40mg/10mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Tyzine Plus 40mg/10mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Tyzine Plus 40mg/10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving:CONSULT YOUR DOCTOR
It is not known whether Tyzine Plus 40mg/10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:CAUTION
Tyzine Plus 40mg/10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tyzine Plus 40mg/10mg Tablet may be needed. Please consult your doctor.
Liver:CAUTION
Tyzine Plus 40mg/10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tyzine Plus 40mg/10mg Tablet may be needed. Please consult your doctor.Regular monitoring of blood pressure is advisable for dose adjustment.
10Drug Tips
Do not take it to treat an acute attack of migraine.
To help prevent migraines, try to eat your meals at the same time every day and avoid bright lights and extreme temperatures. Stay away from loud music and noisy places, and limit foods like chocolate, cheese, and processed items, as well as smoking. Getting enough sleep and managing stress can also reduce the chances of a migraine.
Tyzine Plus 40mg/10mg Tablet is best taken at night before going to bed.
References
Sources and references
Flunarizine [Summary of Product Characteristics]. High Wycombe, Buckinghamshire: Janssen Cilag Ltd.; 2014. [Accessed 10 Mar. 2025] (online) Available from: View
Propranolol and Flunarizine [Product Information]. Punjab, India: Jabs Biotech Pvt. Ltd. [Accessed 04 Mar. 2025] (online) Available from: View
Propranolol and Flunarizine [Product Information]. Mohali, India: Kabir Lifesciences. [Accessed 04 Mar. 2025] (online) Available from: View
Propranolol and Flunarizine [Product Information]. Punjab, India: Vee Remedies; [Accessed 04 Mar. 2025] (online) Available from: View
