Udofix 300mg Tablet

Composition Ursodeoxycholic Acid (300mg)
Rx Prescription Required
Pack strip of 15 tablets
Storage Store below 30°C
Chemical Class Bile Acids and Salts
Action Class Hepatoprotective Agents
Habbit Forming
Manufacturer Morepen Laboratories Ltd
Manufacturer address 409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi – 110 001

Udofix 300mg Tablet is a medicine used to dissolve certain gallstones and prevent them from forming. It helps break down the cholesterol that has converted into stones in your gallbladder, thereby dissolving the stones. It is also used to treat a type of liver disease called primary biliary cirrhosis.

Udofix 300mg Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your health condition. Take it regularly to get maximum benefit, and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.

The most common side effects of Udofix 300mg Tablet are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them or they do not go away, let your doctor know. They may be able to suggest ways to manage them or prescribe an alternative medicine.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, frequent cramp-like pain in your upper abdomen, coughing up blood, or gaining weight rapidly. Using this medicine can reduce or increase the effect of some other medicines, so tell your doctor about all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctor before using this medicine to make sure it is safe for them.

Treatment of Gallbladder stones

Treatment of Primary biliary cirrhosis

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Udofix 300mg Tablet is to be taken with food.

Udofix 300mg Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Q: What if you forget to take Udofix Tablet?
A: If you miss a dose of Udofix 300mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

Udofix 300mg Tablet should be taken after a meal with a glass of milk or water.

Eat a healthy diet, exercise regularly, and avoid alcohol intake.

Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.

Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy and every 6 months thereafter.

Do not stop taking the medication without talking to your doctor.

Q. When should I take Udofix 300mg Tablet?

The suitable timing of taking this medicine might differ depending on your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest taking the last dose at bedtime. Udofix 300mg Tablet should be taken with water or milk after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night.

Q. Is Udofix 300mg Tablet safe?

Udofix 300mg Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose, and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

Q. How does Udofix 300mg Tablet help the liver?

Udofix 300mg Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Q. Does Udofix 300mg Tablet cause weight gain?

Yes, there is a chance of weight gain with Udofix 300mg Tablet, but it is not common. The use of Udofix 300mg Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in the small bile ducts of the liver. In such conditions, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending on the disease, so consult your doctor if you experience weight gain.

Q. What should I avoid while taking Udofix 300mg Tablet?

While taking Udofix 300mg Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Udofix 300mg Tablet. You should also avoid medicines like cholestyramine or colestipol, as they affect the effectiveness of Udofix 300mg Tablet. Ask your doctor about the time gap that should be maintained between Udofix 300mg Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones, and blood cholesterol-lowering agents such as clofibrate, as they may increase the chances of developing gallstones and act opposite to the Udofix 300mg Tablet.

In Treatment of Gallbladder stones

Udofix 300mg Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

Abdominal pain

Diarrhea

Hair loss

Itching

Nausea

Rash

Alcohol:CAUTION

Caution is advised when consuming alcohol with Udofix 300mg Tablet. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Udofix 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CAUTION

Udofix 300mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving:SAFE

Udofix 300mg Tablet does not usually affect your ability to drive.

Kidney:CONSULT YOUR DOCTOR

There is limited information available on the use of Udofix 300mg Tablet in patients with kidney disease. Please consult your doctor.

Liver:CAUTION

Udofix 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Udofix 300mg Tablet may be needed. Please consult your doctor.

Ursodiol [Prescribing Information]. Birmingham, Alabama: Axcan Pharma US, Inc.; 2009. [Accessed 25 Jan. 2019] (online) Available from: View
Ursodiol [Prescribing Information]. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 2013. [Accessed 28 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from: View
Ursodeoxycholic [Package Insert]. Mumbai, India: Alkem Laboratories Ltd.; 2016. [Accessed 07 Aug. 2023]. (online) Available from: View
The Lancet. Gastroenterology and Hepatology. [Accessed 07 Aug. 2023]. (online) Available from: View
Ursodeoxycholic Acid [Package Insert]. Hertfordshire, UK: Glenmark Pharmaceuticals Europe Limited; 2019. [Accessed 03 Feb. 2025]. (online) Available from: View