Xalipat 100 Injection

Composition Oxaliplatin (100mg)
Rx Prescription Required
Pack vial of 1 Injection
Storage Store below 25°C
Chemical Class Platinum Analogs
Action Class Platinum-Based Alkylating Agents
Habbit Forming
Manufacturer Khandelwal Laboratories Pvt Ltd
Manufacturer address KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA

Xalipat 100 Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Xalipat 100 Injection is given as an injection into vein by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.

Cancer of colon and rectum

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Xalipat 100 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

Q: What if you forget to take Xalipat Injection?
A: If you miss a dose of Xalipat 100 Injection, please consult your doctor.

Xalipat 100 Injection is given as an injection into veins under the supervision of a doctor.

Xalipat 100 Injection is given as an injection into veins under the supervision of a doctor.

Abdominal pain

Injection site reaction

Weight gain

Conjunctivitis

Fever

Nosebleeds

Hair loss

Constipation

Skin disorder

Decreased appetite

Infection

Peripheral sensory neuropathy

Inflammation of the nose

Pain

Increased transaminase level in blood

Increased alkaline phosphatase level in blood

Taste change

Edema (swelling)

Lacrimation disorder

Allergic reaction

Fatigue

Nausea

Vomiting

Diarrhea

Stomatitis (Inflammation of the mouth)

Anemia (low number of red blood cells)

Decreased white blood cell count (neutrophils)

Low blood platelets

Headache

Breathlessness

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xalipat 100 Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Xalipat 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Xalipat 100 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Xalipat 100 Injection may cause side effects which could affect your ability to drive.Xalipat 100 Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.

Kidney:CAUTION

Xalipat 100 Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Xalipat 100 Injection may be needed. Please consult your doctor.Limited information is available on the use of Xalipat 100 Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver:CAUTION

Xalipat 100 Injection should be used with caution in patients with liver disease. Dose adjustment of Xalipat 100 Injection may be needed. Please consult your doctor.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from: View
Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from: View