Xariban 10 Tablet

Composition Rivaroxaban (10mg)
Rx Prescription Required
Pack strip of 10 tablets
Storage Store below 30°C
Chemical Class Morpholine & thiophene derivative
Action Class Oral Factor Xa Inhibitors
Habbit Forming
Manufacturer Benedis Life Sciences
Manufacturer address 127/742, W BLOCK BASANT VIHAR KANPUR Kanpur UP 208021 IN

Xariban 10 Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart.

Xariban 10 Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It may be taken with or without food. Take it at the same time each day for maximum benefits. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Xariban 10 Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Treatment and prevention of Blood clots

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xariban 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Xariban 10 Tablet is a novel oral anticoagulant (NOAC). It works by stopping a clotting factor called factor Xa from working. This helps prevent the formation of blood clots in the body.

Q: What if you forget to take Xariban Tablet?
A: If you miss a dose of Xariban 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

For best results, take Xariban 10 Tablet at the same time every day. It is better to take at night with meals.

It interacts less with food or other medicines. Hence, frequent dose changes are not required.

It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).

It may cause dizziness. Avoid driving or activity requiring mental focus until you know how it affects you.

If you are going to have a surgery or dental treatment, you may be asked to stop taking Xariban 10 Tablet temporarily.

Notify your doctor if you have any kidney problem.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Do not stop taking medication without talking to your doctor.

Q. What are the side effects of Xariban 10 Tablet?

The most common side effects of Xariban 10 Tablet include long or excessive bleeding, breathlessness (which may be a sign of bleeding), exceptional weakness, tiredness, paleness, dizziness, headache, and unexplained swelling. Other side effects can be severe skin and allergic reactions, bruising, coughing up blood, bleeding from the skin or under the skin, and swelling and pain in the limbs. Using Xariban 10 Tablet may increase the bilirubin and decrease the number of platelets. Some people may experience fainting episodes, faster heartbeat, and dry mouth. In case you notice any side effects, immediately contact your doctor.

Q. Is Xariban 10 Tablet a blood thinner?

Yes, Xariban 10 Tablet is a blood thinner. It is a medication that prevents the blood from clotting within the blood vessels. It also prevents the blood clots from recurring in the blood vessels. It may be prescribed to treat blood clots in the veins of the legs and in the blood vessels of the lungs.

Q. Is Xariban 10 Tablet dangerous?

Xariban 10 Tablet has numerous beneficial effects, but it has a tendency to make you bleed more than normal come even with minor injuries as it reduces your blood’s clotting ability. Sometimes Xariban 10 Tablet may cause serious bleeding which may be dangerous and may need urgent medical attention. This risk may be higher in people taking Xariban 10 Tablet along with other blood thinning medications. Contact your doctor if you notice even minor bleeding.

Q. What foods should you avoid if you are on blood thinners?

Avoid taking grapefruit and grapefruit juice while taking Xariban 10 Tablet. The reason being, grapefruit contains compounds that slow down the metabolism of Xariban 10 Tablet and increase the activity leading to bleeding. On the other hand, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the activity of vitamin K or increases the clotting of blood. Such food items may include spinach, brussels, sprouts, mustard greens, broccoli, asparagus and green tea. However, the use of these food items is not restricted with Xariban 10 Tablet.

In Treatment and prevention of Blood clots

Xariban 10 Tablet is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. Xariban 10 Tablet can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism) or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.

Bleeding

Alcohol:CAUTION

Caution is advised when consuming alcohol with Xariban 10 Tablet. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Xariban 10 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Xariban 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Xariban 10 Tablet may cause side effects which could affect your ability to drive.Xariban 10 Tablet may cause dizziness or fainting. This may affect your driving ability.

Kidney:CAUTION

Xariban 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xariban 10 Tablet may be needed. Please consult your doctor.Use of Xariban 10 Tablet is not recommended in patients with severe kidney disease.

Liver:UNSAFE

Xariban 10 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 365-66.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1228.
Rivaroxaban. Gurabo, Puerto Rico: Janssen Ortho, LLC; 2014. [Accessed 20 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rivaroxaban. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). Rivaroxaban. [Accessed 19 Mar. 2019] (online) Available from: View