Zolfem 2% Cream

Composition Ketoconazole (2% w/w)
Rx Prescription Required
Pack tube of 30 gm Cream
Storage Store below 30°C
Chemical Class Azole derivatives {Imidazoles}
Action Class Fungal Ergosterol Synthesis Inhibitor
Habbit Forming
Manufacturer Next Wave India
Manufacturer address Next Wave (India) S.C.O. No. 313, 2nd Floor, Gurugram – 122002 Haryana INDIA

Zolfem 2% Cream is an antifungal medication applied to the skin to treat fungal infections like athlete’s foot, ringworm, jock itch, and yeast infections. It works by stopping the growth of fungus, helping to clear the infection and relieve symptoms like itching, redness, and scaling.

Use Zolfem 2% Cream in the dose and duration prescribed by your doctor. Continue using the medicine for the full prescribed time, even if symptoms improve, to prevent the infection from coming back. Keep the affected area clean and dry, avoid sharing personal items like towels, and wear loose, breathable clothing to help the skin heal faster.

Zolfem 2% Cream is usually well-tolerated, but some people may experience mild side effects like skin burning, itching, or redness at the application site. If these occur, try using the medication less often or consult your doctor. Avoid scratching the area, as this can worsen irritation. To minimize side effects, apply only as directed and avoid using it on broken or sensitive skin unless instructed by your doctor.

Before using Zolfem 2% Cream, inform your doctor if you have allergies or sensitive skin. Avoid contact with the eyes, nose, mouth, or open wounds, as it may cause irritation. Do not cover the treated area with tight bandages unless advised by your doctor, as this can increase absorption and side effects. If you are pregnant or breastfeeding, consult a doctor before use. If your condition does not improve after a few weeks or gets worse, seek medical advice.

Treatment of Fungal skin infections

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

Zolfem 2% Cream is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

Q: What if you forget to take Zolfem Cream?
A: If you miss a dose of Zolfem 2% Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Don’t stop early, keep using it for the full treatment time, even if the infections improve. Stopping too soon can lead to the infection coming back.

Wash your hands after applying (unless treating hands) to avoid spreading the infection.

Avoid tight clothing and wear loose, breathable fabrics to keep the area dry and prevent irritation.

Do not share towels, clothes, or personal items; fungal infections can spread easily.

Zolfem 2% Cream may make the skin more sensitive to sunlight. Use sunscreen or cover treated areas when going outside.

Q. What is Zolfem 2% Cream used for?

Zolfem 2% Cream is an antifungal medicine that treats various skin infections including athlete’s foot, ringworm, jock itch, and yeast infections. It works by stopping fungal growth and helps relieve symptoms like itching, redness, and flaking skin.

Q. How long until I see results from using Zolfem 2% Cream?

While some improvement in symptoms like itching and redness may be noticeable within a few days, complete healing typically takes between 2 to 6 weeks of consistent use. It is crucial to continue treatment for the full prescribed duration even after symptoms disappear to prevent the infection from returning.

Q. Is Zolfem 2% Cream safe to use on broken skin?

You should generally avoid applying Zolfem 2% Cream to open wounds or severely damaged skin unless specifically instructed by your doctor, as it may cause additional irritation. For minor cuts or abrasions near the affected area, apply carefully around them.

Q. What side effects might I experience?

Some users report mild skin irritation, burning sensations, itching, or dryness where the medication is applied. These effects are usually temporary. However, if you develop severe reactions like significant swelling, intense redness, or blistering, discontinue use immediately and consult your healthcare provider.

Q. Can pregnant or breastfeeding women use Zolfem 2% Cream?

While topical ketoconazole is generally considered low-risk, pregnant or breastfeeding women should consult their doctor before using this medication to weigh potential benefits against any possible risks.

Q. Can I apply other skin products over Zolfem 2% Cream?

You may use makeup, moisturizers, or sunscreen after applying Zolfem 2% Cream, but wait at least 10-15 minutes to allow the medication to be fully absorbed into the skin first.

Q. How can I prevent fungal infections from recurring?

Maintain good skin hygiene by keeping affected areas clean and dry. Avoid sharing personal items like towels or clothing. For foot infections, consider using antifungal powder in shoes and socks. Wearing breathable fabrics like cotton can also help prevent reinfection.

Q. Is Zolfem 2% Cream appropriate for children?

While Zolfem 2% Cream can be used in pediatric patients, it should only be administered under medical supervision. The appropriate dosage and treatment duration may vary depending on the child’s age and the severity of the infection.

Q. What precautions should I take while using Zolfem 2% Cream?

Take care to avoid contact with the eyes, nose, and mouth. Unless directed by your doctor, don’t cover treated areas with airtight bandages, as this may increase absorption and side effects. Be mindful that it may increase sun sensitivity in some people, so take appropriate sun protection measures.

Q. Can I stop treatment once my symptoms improve?

No, you should complete the full course of treatment exactly as prescribed. Stopping early, even if symptoms disappear, may allow surviving fungi to regrow and cause the infection to return.

In Treatment of Fungal skin infections

Zolfem 2% Cream is an antifungal medicine that treats skin infections caused by fungi. It works by killing the fungi and stopping their growth, helping to clear the infection and relieve symptoms like itching, redness, and scaling. For best results, use this medicine for the full prescribed duration, even if your symptoms improve, to prevent the infection from returning. Depending on the infection, treatment may take several weeks. In some cases, occasional application may be needed even after the infection clears to prevent recurrence.

Application site redness

Application site itching

Application site burning

Alcohol:

No interaction found/established

Pregnancy:SAFE IF PRESCRIBED

Zolfem 2% Cream is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:SAFE IF PRESCRIBED

Zolfem 2% Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving:

No interaction found/established

Kidney:

No interaction found/established

Liver:

No interaction found/established

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1576.
Ketoconazole cream [Prescribing Information]. Hawthorne, NY: Taro Pharmaceuticals Inc.; 2014. [Accessed 10 Jun. 2025] (online) Available from: View
Ketoconazole [Summary of Product Characteristics]. Alwar, Rajasthan: Kusum Healthcare Pvt. Ltd.; 2023. [Accessed 10 Jun. 2025] (online) Available from: View