Zytor-Plus 10 Tablet

Zytor-Plus 10 Tablet is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension.

It is best to take Zytor-Plus 10 Tablet in the morning along with food to avoid frequent urination at night. For better results, it is suggested that you take it at the same time every day. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

Common side effects of Zytor-Plus 10 Tablet include dizziness, frequent urination, headache, diarrhea, and period pain. If any of these side effects persist or worsen, let your doctor know. They may be able to suggest ways to manage or treat them.
Before taking this medicine, tell your doctor if you have any liver or kidney disease. Tell your doctor if you are pregnant or breastfeeding. You should also let your doctor know all other medicines you are taking, as they may affect, or be affected by, this medicine.

Treatment of Edema

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zytor-Plus 10 Tablet is to be taken with food.

Zytor-Plus 10 Tablet works by removing excess fluid and reducing blood pressure while maintaining the body’s potassium balance. Torasemide, a diuretic, helps the kidneys eliminate extra salt and water, reducing swelling and lowering blood pressure. Spironolactone, a potassium-sparing diuretic, prevents excessive potassium loss while also helping remove excess fluid. Together, they help treat conditions like fluid buildup (edema) without causing major electrolyte imbalances.

Q: What if you forget to take Zytor-Plus Tablet?
A: If you miss a dose of Zytor-Plus 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Take it in the morning with breakfast to avoid getting up at night to urinate.

It may cause dizziness or sleepiness. Don’t drive or do anything requiring concentration until you know how it affects you.

To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Your doctor may regularly monitor your blood pressure, kidney function, and the level of salts such as potassium and sodium in your blood while you’re taking this medication.

Q. What is Zytor-Plus 10 Tablet?

Zytor-Plus 10 Tablet is a fixed-dose combination of torasemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics, and they help to remove excess fluid from the body. This medicine is prescribed for individuals with edema.

Q. Is it safe to use Zytor-Plus 10 Tablet?

Yes, Zytor-Plus 10 Tablet is safe to use in most patients. However, in some patients, it may cause common side effects like dizziness, frequent urge to urinate, and headache. Inform your doctor if you experience any persistent problems while taking this medicine.

Q. Can the use of Zytor-Plus 10 Tablet cause dizziness?

Yes, the use of Zytor-Plus 10 Tablet can cause dizziness (feeling faint, weak, unsteady, or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Q. Can the use of Zytor-Plus 10 Tablet cause dehydration (excessive loss of fluid)?

Yes, the use of Zytor-Plus 10 Tablet can cause dehydration (excessive loss of fluid). Inform your doctor if you experience persistent problems while taking this medicine.

Q. Can the use of Zytor-Plus 10 Tablet cause hyperkalemia (increased potassium levels)?

Yes, Zytor-Plus 10 Tablet can cause hyperkalemia (increased potassium levels). This occurs more commonly in patients with underlying kidney disease or patients taking excessive potassium in their diet. High potassium levels can cause fatal heart problems. It is very important to get electrolytes and kidney function tests done regularly while you are taking this medicine.

Q. What are the contraindications to the use of Zytor-Plus 10 Tablet?

The use of Zytor-Plus 10 Tablet should be avoided in patients with hypersensitivity to torasemide, sulfonylureas, spironolactone, or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs that cause renal damage, patients with high potassium levels (hyperkalemia), Addison’s disease, and in children with moderate to severe renal impairment.

Q. What is the storage condition for the Zytor-Plus 10 Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

In Treatment of Edema

Edema means swelling of the body due to excess water. Swelling usually occurs in the feet, legs, arms but it can involve your whole body. Zytor-Plus 10 Tablet reduces swelling by increasing the amount of urine produced. This helps your body get rid of extra water and treats edema. Zytor-Plus 10 Tablet helps maintain the level of potassium in the body. Altogether, this will help you go about your daily activities more easily and make you more confident about being active. Take it regularly and make appropriate lifestyle changes to help this medicine be more effective.

Dizziness

Frequent urge to urinate

Headache

Inflammation of the nose

Muscle pain

Gastrointestinal disturbance

Increased liver enzymes

Diarrhea

Memory impairment

Pain during periods

Abnormal ECG

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zytor-Plus 10 Tablet. Please consult your doctor.

Pregnancy:SAFE IF PRESCRIBED

Zytor-Plus 10 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding:CONSULT YOUR DOCTOR

Information regarding the use of Zytor-Plus 10 Tablet during breastfeeding is not available. Please consult your doctor.

Driving:CONSULT YOUR DOCTOR

It is not known whether Zytor-Plus 10 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney:CAUTION

Zytor-Plus 10 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zytor-Plus 10 Tablet may be needed. Please consult your doctor.Use of Zytor-Plus 10 Tablet is not recommended in patients with severe kidney disease.

Liver:CAUTION

Zytor-Plus 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zytor-Plus 10 Tablet may be needed. Please consult your doctor.

Torsemide [Prescribing Information]. Leganes Spain: Roche Farma S.A.; 2010. [Accessed 11 Apr. 2019] (online) Available from: View
Torsemide and Spironolactone Tablets [Patient Information]. Ahmedabad, India: Torrent Pharmaceuticals Ltd.; 2015. [Accessed 28th Sept. 2023] (online) Available from: View
Torsemide and Spironolactone [Patient Information]. Punjab, India: Scott Morrison;. [Accessed 06th Mar. 2025] (online) Available from: View