Ab-Taxomed Injection
Ab-Taxomed Injection is an anti-cancer medication that may be used in combination with other medicines. It is used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer in adults.
Ab-Taxomed Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Ab-Taxomed Injection is an anti-cancer medication that may be used in combination with other medicines. It is used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer in adults.
Ab-Taxomed Injection is an anti-cancer medication that may be used in combination with other medicines. It is used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer in adults.
Ab-Taxomed Injection is given as an injection by a trained healthcare professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. It should be used exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but the treatment should not be stopped unless your doctor tells you to.
Some common side effects of this medicine include nausea, vomiting, diarrhea, and weakness. It may also cause serious side effects such as swelling of hands or lips, hair loss, and nerve problems. To reduce these side effects your doctor may suggest some medications along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Treatment of Breast cancer
Treatment of Non-small cell lung cancer
Treatment of Pancreatic cancer
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Ab-Taxomed Injection is a combination of two medicines: paclitaxel and albumin. Paclitaxel, an anticancer chemical derived from plants, works by stopping cancer cells from separating into two new cells. This blocks the growth of the cancer. Albumin, a natural protein in blood, works by replacing the blood or body fluids lost due to excessive bleeding, surgery, or kidney dialysis.
06What If You Miss A Dose?
Q: What if you forget to take Ab-Taxomed Injection?
A: If you miss a dose of Ab-Taxomed Injection, consult your doctor.
07Benefits
In Treatment of Breast cancer
Ab-Taxomed Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Ab-Taxomed Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
08Side Effects
Hair loss
Decreased white blood cell count (neutrophils)
ECG changes
Fatigue
Muscle pain
Joint pain
Increased aspartate aminotransferase
Increased alkaline phosphatase level in blood
Anemia (low number of red blood cells)
Infection
Diarrhea
Low blood platelets
Peripheral neuropathy (tingling and numbness of feet and hand)
Nausea
Vomiting
Peripheral edema
Fever
Decreased appetite
Rash
Dehydration
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ab-Taxomed Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Ab-Taxomed Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Ab-Taxomed Injection during breastfeeding is not available. Please consult your doctor.
Driving:CONSULT YOUR DOCTOR
It is not known whether Ab-Taxomed Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Ab-Taxomed Injection in patients with kidney disease. Please consult your doctor.
Liver:CAUTION
Ab-Taxomed Injection should be used with caution in patients with liver disease. Dose adjustment of Ab-Taxomed Injection may be needed. Please consult your doctor.
10Drug Tips
Ab-Taxomed Injection may cause birth defects if either the male or female is treated with it at the time of conception. You should use some kind of birth control while being treated with this medicine and for at least 12 weeks after you stop using it.
If you receive Ab-Taxomed Injection in combination with gemcitabine, infections can be severe and lead to death. Tell your doctor immediately if you have a fever (temperature greater than 100.4° F) or develop signs of infection.
Be careful when using a toothbrush, toothpick, or dental floss. Your doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Also, avoid contact sports or other situations where you may bruise or get injured since this medicine increases the risk of bleeding.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Decreased sensation, numbness, and tingling in fingers and toes may worsen with repeated doses of this medicine. Protect yourself from injury if you have numb hands or feet, and report this to your doctor.
If you are undergoing any surgery, let the surgeon or anesthetist know that you are being treated with Ab-Taxomed Injection since it may affect other medicines used during surgery.
References
Sources and references
Paclitaxel and human albumin [Patient Information Leaflet]. New Jersey, US: Celgene Corporation Summit; 2022. [Accessed 15 Nov. 2022]. (online) Available from: View
Paclitaxel and albumin [Prescribing Information]. [Accessed 15 Nov. 2022]. (online) Available from: View
Paclitaxel and human albumin [Consumer Medicine Information]. Abraxis BioScience, LLC; 2018. [Accessed 15 Nov. 2022]. (online) Available from: View
Weaver BA. How Taxol/paclitaxel kills cancer cells. Mol Biol Cell. 2014;25(18):2677-81. [Accessed 15 Nov. 2022]. (online) Available from: View
