Abirakast 250mg Tablet
Abirakast 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Abirakast 250mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Abirakast 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Abirakast 250mg Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Abirakast 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, fatigue and increased liver enzymes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
03Uses
Prostate cancer
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abirakast 250mg Tablet is to be taken empty stomach.
05How It Works
Abirakast 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.
06Benefits
In Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Abirakast 250mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
07Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Altered blood sugar level
Increased levels of blood fat
Joint swelling
Hypercholesterolemia (high cholesterol)
Cough
High blood pressure
Diarrhea
Urinary tract infection
Anemia (low number of red blood cells)
Increased liver enzymes
Fatigue
Decreased white blood cell count
Decreased potassium level in blood
Vomiting
Edema (swelling)
08Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abirakast 250mg Tablet. Please consult your doctor.
Pregnancy:UNSAFE
Abirakast 250mg Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:UNSAFE
Abirakast 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:SAFE
Abirakast 250mg Tablet does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Abirakast 250mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Abirakast 250mg Tablet is recommended.Because of the limited information, cautious use of Abirakast 250mg Tablet is recommended in patients with severe kidney disease.
Liver:CAUTION
Abirakast 250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Abirakast 250mg Tablet may be needed. Please consult your doctor.
09Drug Tips
Abirakast 250mg Tablet treats prostate cancer that has spread to other parts of the body.
It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
It must be taken on an empty stomach. Don’t eat any food for at least 2 hours before or 1 hour after your dose.
Always use effective birth control measures to prevent pregnancy while taking this medicine.
Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.
References
Sources and references
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. view
Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 . view
Central Drugs Standard Control Organisation . view
