Active B12 PG Tablet SR
Active B12 PG Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating the calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heals damaged nerve cells.
Active B12 PG Tablet SR
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Active B12 PG Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating the calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heals damaged nerve cells.
Active B12 PG Tablet SR is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating the calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heals damaged nerve cells.
Active B12 PG Tablet SR may be taken with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor.
Some common side effects of this medicine include nausea, vomiting, diarrhea, constipation, blurred vision, dizziness, and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild and usually improve with time. It may also cause weight gain in some people. Exercise regularly and have a balanced diet to keep your weight in check. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding to make sure it is safe for you and the developing baby.
03Uses
Treatment of Neuropathic pain
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Active B12 PG Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Active B12 PG Tablet SR is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B, which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha-2 delta ligand that decreases pain by modulating the calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
06What If You Miss A Dose?
Q: What if you forget to take Active B12 PG Tablet SR?
A: If you miss a dose of Active B12 PG Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Neuropathic pain
Active B12 PG Tablet SR is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction. Taking Active B12 PG Tablet SR regularly will improve your physical and social functioning and overall quality of life.
08Side Effects
Decreased appetite
Nausea
Vomiting
Diarrhea
Headache
Blurred vision
Constipation
Dizziness
Drowsiness
Fatigue
Weight gain
09Safety Information
Alcohol:UNSAFE
Active B12 PG Tablet SR may cause excessive drowsiness with alcohol.
Pregnancy:CONSULT YOUR DOCTOR
Active B12 PG Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Active B12 PG Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Active B12 PG Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CAUTION
Active B12 PG Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Active B12 PG Tablet SR may be needed. Please consult your doctor.
Liver:SAFE IF PRESCRIBED
Active B12 PG Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Active B12 PG Tablet SR may not be needed in these patients. Please consult your doctor.
10Drug Tips
Active B12 PG Tablet SR may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid consuming alcohol when taking Active B12 PG Tablet SR, as it may cause excessive sleepiness.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.
Active B12 PG Tablet SR may cause weight gain. Exercise regularly and eat a balanced diet to manage it.
References
Sources and references
Pregabalin [Prescribing Information]. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from: View
Pregabalin [Prescribing Information]. New York, NY: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Apr. 2019] (online) Available from: View
Methylcobalamin and pregabalin [Patient Information]. Pune, Maharashtra: Epion Pharmaceuticals Pvt. Ltd.; [Accessed 14 Apr. 2025] (online) Available from: View
Methylcobalamin and pregabalin [Patient Information]. Ahmedabad, Gujarat: West Coast Pharmaceutical Works Ltd.; [Accessed 14 Apr. 2025] (online) Available from: View
