Adsunib 12.5 Capsule
Adsunib 12.5 Capsule is used in the treatment of kidney cancer and gastrointestinal stromal tumor.
Adsunib 12.5 Capsule
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Adsunib 12.5 Capsule is used in the treatment of kidney cancer and gastrointestinal stromal tumor.
Adsunib 12.5 Capsule is used in the treatment of kidney cancer and gastrointestinal stromal tumor.
Adsunib 12.5 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.Nausea, vomiting, weakness and weight loss are some common side effects of this medicine. The doctor may advise for regular monitoring of blood pressure and thyroid gland function while taking this medicine. It may decrease blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, if you are diabetic then it is important to check your blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted. This medicine may affect wound healing time, so be careful while shaving, cutting fingernails or using sharp objects.Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or bleeding disorder. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Kidney cancer
Gastrointestinal stromal tumour
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Adsunib 12.5 Capsule may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Adsunib 12.5 Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.
06What If You Miss A Dose?
If you miss a dose of Adsunib 12.5 Capsule, skip it and continue with your normal schedule. Do not double the dose.
07Benefits
In Kidney cancer
Adsunib 12.5 Capsule is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
In Gastrointestinal stromal tumour
A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Adsunib 12.5 Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Breathlessness
Taste change
Cough
Weight loss
Joint pain
Headache
Back pain
Pain in extremity
Hair discoloration
Stomatitis (Inflammation of the mouth)
Painful blisters on hands and feet
Constipation
Diarrhea
High blood pressure
Dry skin
Fever
Fatigue
Discoloration of skin
Indigestion
Abdominal pain
Rash
Weakness
Vomiting
Nausea
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adsunib 12.5 Capsule. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Adsunib 12.5 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Adsunib 12.5 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Adsunib 12.5 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:SAFE IF PRESCRIBED
Adsunib 12.5 Capsule is safe to use in patients with kidney disease. No dose adjustment of Adsunib 12.5 Capsule is recommended.
Liver:CAUTION
Adsunib 12.5 Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Adsunib 12.5 Capsule may be needed. Please consult your doctor.Limited information is available on the use of Adsunib 12.5 Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
10Drug Tips
Adsunib 12.5 Capsule is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Monitoring of thyroid gland function is required while taking this medicine. Inform your doctor if you notice symptoms of weight gain, dry skin, and hair.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Inform your doctor about the consumption of Adsunib 12.5 Capsule before going for surgical procedure.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
References
Sources and references
Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1304.
Sunitinib malate. New York, New York: Pfizer Inc.; 2006 . view
Drugs.com. Sunitinib Pregnancy and Breastfeeding Warnings. view
Sunitinib malate. Sandwich, Kent: Pfizer Limited; 2006 . view
Central Drugs Standard Control Organisation . view
