Afayro 40 Tablet
Afayro 40 Tablet is used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain mutations of epidermal growth factor receptor (EGFR).
Afayro 40 Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Afayro 40 Tablet is used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain mutations of epidermal growth factor receptor (EGFR).
Afayro 40 Tablet is used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain mutations of epidermal growth factor receptor (EGFR).
Afayro 40 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include diarrhea, rash, dry skin, and nausea. Diarrhea can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for some blood tests while you are taking this medicine. It may also make your skin sensitive to the sun, so use sunscreen and wear protective clothing if you have to be in sunlight. Inform your doctor if you notice pain or redness in the eye or dry eye.
Before taking it, tell your doctor if have a breathing problem, liver, or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.
03Uses
Non-small cell lung cancer
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afayro 40 Tablet is to be taken empty stomach.
05How It Works
Afayro 40 Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it to stop or slow the spread of cancer.
06What If You Miss A Dose?
Q: What if you forget to take Afayro Tablet?
A: If you miss a dose of Afayro 40 Tablet, skip it and continue with your normal schedule. Do not double the dose.
07Benefits
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Afayro 40 Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
08Side Effects
Diarrhea
Rash
Dry skin
Nausea
Vomiting
Loss of appetite
Itching
Stomatitis (Inflammation of the mouth)
Nail disorder
09Safety Information
Alcohol:SAFE
Consuming alcohol with Afayro 40 Tablet does not cause any harmful side effects.
Pregnancy:CONSULT YOUR DOCTOR
Afayro 40 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Afayro 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:CONSULT YOUR DOCTOR
It is not known whether Afayro 40 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:SAFE IF PRESCRIBED
Afayro 40 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Afayro 40 Tablet may not be needed in these patients. Please consult your doctor.
Liver:SAFE IF PRESCRIBED
Afayro 40 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Afayro 40 Tablet may not be needed in these patients. Please consult your doctor.
10Drug Tips
You have been prescribed Afayro 40 Tablet for the treatment of certain type of lung cancer (non-small cell lung cancer).
Take Afayro 40 Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal.
Diarrhea is common with Afayro 40 Tablet and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed.
Afayro 40 Tablet can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight.
Afayro 40 Tablet can cause redness, rash, and acne. Get treatment for skin reactions as soon as you notice them.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Afayro 40 Tablet is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
References
Sources and references
Afatinib. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2013. [Accessed 03 Jul. 2019] (online) Available from: View
Gilotrif. Afatinib. [Accessed 26 Mar. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: View
