AMARYL P 15 MG/1 MG TABLET

AMARYL P 15 MG/1 MG TABLET should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop edema (swelling), cold symptoms, headache, urinary tract infection, diarrhea, nausea, leg pain, reduced blood cell count, infection, and accidental injury. However, these are temporary and usually subside on their own. If these do not resolve or bother you, please consult your doctor.

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

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AMARYL P 15 MG/1 MG TABLET is an anti-diabetic medication. It works by increasing the body’s sensitivity to insulin, a natural substance that helps control blood sugar levels.

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Pioglitazone helps to control blood sugar level and avoid long-term complications.

You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Pioglitazone.

Take it only as per dose and duration suggested by your doctor. 

Full effects may be visible after several weeks of starting Pioglitazone. Keep taking it as prescribed by your doctor. 

Monitor your blood sugar level regularly while taking this medicine. 

Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.

Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite. 

Q. Can Pioglitazone cause weight gain?

Pioglitazone commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.

Q. Can Pioglitazone cause heart failure?

Pioglitazone can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Pioglitazone is used with insulin.

Q. Can you take Pioglitazone and metformin together?

Yes, Pioglitazone can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.

Q. What time of day should you take Pioglitazone?

It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Pioglitazone exactly as prescribed by your doctor.

Q. How long do I need to take Pioglitazone? Can I stop the medicine for some time?

Continue taking Pioglitazone as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.

Q. Can Pioglitazone cause bladder cancer?

Pioglitazone may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Pioglitazone should not be used in patients with a prior history of bladder cancer or having bladder cancer.

Q. Does Pioglitazone affect liver?

Yes, Pioglitazone may cause an increase in liver enzymes, and treatment with Pioglitazone should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Pioglitazone should not be prescribed to patients with liver disease.

Q. What kind of medicine is Pioglitazone? Is it like metformin?

Pioglitazone belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Q. Does Glimepiride make you sleepy?

Glimepiride itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.

Q. Is Glimepiride safe for kidneys?

Glimepiride does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Glimepiride is principally eliminated by the kidneys.

Q. Does Glimepiride cause memory loss?

No, it is not known that Glimepiride causes memory loss. However, the use of Glimepiride may cause low blood sugar which may cause problems with concentration and reduced alertness.

Q. Who should not take Glimepiride?

Glimepiride should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Glimepiride.

Q. How long does it take for Glimepiride to start working?

Glimepiride takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.

Q. How long do I need to take Glimepiride? Can I stop the medication?

Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Glimepiride only controls the sugar levels but does not cure it. Do not stop taking Glimepiride without talking to your doctor. If you stop taking Glimepiride suddenly your diabetes may get worse.

Q. How and when to take Glimepiride?

Glimepiride is advised to be taken in the dose and duration suggested by your doctor. Generally, a single daily dose of Glimepiride is sufficient to control blood sugar levels. The dose should be taken whole with water shortly before or during breakfast. However, if you skip breakfast then the medicine should be taken shortly before or during your first main meal.

Q. What can happen if I take more than the recommended dose of Glimepiride?

Glimepiride should be taken strictly as advised by the doctor. Overdose of Glimepiride may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Dizziness

Nausea

Headache

Hypoglycemia (low blood glucose level)

Alcohol:UNSAFE

It is unsafe to consume alcohol with AMARYL P 15 MG/1 MG TABLET.

Pregnancy:CONSULT YOUR DOCTOR

AMARYL P 15 MG/1 MG TABLET may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:SAFE IF PRESCRIBED

AMARYL P 15 MG/1 MG TABLET is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.Monitoring of the breastfed infant’s blood glucose is advisable during maternal therapy with AMARYL P 15 MG/1 MG TABLET

Driving:CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney:CAUTION

AMARYL P 15 MG/1 MG TABLET should be used with caution in patients with kidney disease. Dose adjustment of AMARYL P 15 MG/1 MG TABLET may be needed. Please consult your doctor.Use of AMARYL P 15 MG/1 MG TABLET is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.

Liver:CAUTION

AMARYL P 15 MG/1 MG TABLET should be used with caution in patients with liver disease. Dose adjustment of AMARYL P 15 MG/1 MG TABLET may be needed. Please consult your doctor.Use of AMARYL P 15 MG/1 MG TABLET is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.

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Pioglitazone hydrochloride. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2000 . view

Drugs.com. Pioglitazone+Glimepiride. view

Mayo Clinic. Pioglitazone and Glimepiride. view

Pioglitazone. County Wicklow, Ireland: Takeda Ireland Limited. view