Amypres 50mg Tablet
Amypres 50mg Tablet is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine.
Amypres 50mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Amypres 50mg Tablet is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine.
Amypres 50mg Tablet is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine.
Amypres 50mg Tablet is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.How long you need to use it will depend on what you are taking it for, but it is important to continue taking this medication even if you feel well. Do not stop taking the medicine suddenly without talking to your doctor. Stopping the medicine suddenly can worsen your conditions or cause other symptoms. Your dose may be modified or gradually decreased before stopping the medication.The most common side effects of this medicine include nausea, constipation, sweating, dry mouth, sleepiness, tremor, dizziness, headache, speech disorder, accommodation disorder, palpitations, increased heart rate, orthostatic hypotension, and nasal congestion. It may also make you aggressive or confused and can lead to weight gain in some people.This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.
03Uses
Treatment of Depression
Neuropathic pain
Treatment of Migraine
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amypres 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Amypres 50mg Tablet contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).
06What If You Miss A Dose?
If you miss a dose of Amypres 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Depression
Amypres 50mg Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of well-being, relieve anxiety and tension, helps you sleep better, and increase your energy level. Amypres 50mg Tablet is readily absorbed and starts action within approximately 6 hours of taking it orally (by mouth). It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.
In Neuropathic pain
Amypres 50mg Tablet helps in relieving neuropathic pain caused by nerve damage in certain conditions. These may include painful diabetic neuropathy, post-herpetic neuralgia, or spinal cord disease. It works by affecting chemicals in the brain called neurotransmitters. By relieving pain, it helps improve your quality of life.
In Treatment of Migraine
Amypres 50mg Tablet helps prevent migraines by changing the way that your nerves receive pain signals. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Difficulty in paying attention
Palpitations
Accomodation disorder
Speech disorder
Tremor
Nausea
Headache
Dizziness
Sweating
Sleepiness
Nasal congestion (stuffy nose)
Aggressive behavior
Weight gain
Increased heart rate
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Dryness in mouth
Constipation
09Safety Information
Alcohol:UNSAFE
It is unsafe to consume alcohol with Amypres 50mg Tablet.
Pregnancy:CONSULT YOUR DOCTOR
Amypres 50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Amypres 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Amypres 50mg Tablet may cause side effects which could affect your ability to drive.Amypres 50mg Tablet may impair your alertness which may affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Amypres 50mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amypres 50mg Tablet may not be needed in these patients. Please consult your doctor.
Liver:CAUTION
Amypres 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amypres 50mg Tablet may be needed. Please consult your doctor.Use of Amypres 50mg Tablet is not recommended in patients with severe liver disease.
10Drug Tips
It may take 4 to 6 weeks for Amypres 50mg Tablet to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Amypres 50mg Tablet as it may cause excessive sleepiness.
Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
References
Sources and references
Stahl SM, editor. Amitriptyline. In: Stahl’s Essential Pschopharmacology: Prescriber’s Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 25-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 58-59.
Amitriptyline. Princeton: Sandoz Inc; 2014. view
Drugs and Lactation Database. Bethesda : National Library of Medicine ; 2006. Amitriptyline. . view
Central Drugs Standard Control Organisation . view
