Aparin 50mg Tablet
Aparin 50mg Tablet works by weakening the body’s immune system, so it does not attack the new organ. The amount of medicine to be taken and how often you need to take it will depend on the type of transplant you have. Follow your doctor’s instructions on this. You should take it along with food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.
Aparin 50mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Aparin 50mg Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis.
Aparin 50mg Tablet works by weakening the body’s immune system, so it does not attack the new organ. The amount of medicine to be taken and how often you need to take it will depend on the type of transplant you have. Follow your doctor’s instructions on this. You should take it along with food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.
It has many potential side effects. The most common are loss of appetite, nausea, and increased risk of bleeding. Because it suppresses your immune system, you may catch infections easily. There’s also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may need urgent medical attention.
Aparin 50mg Tablet can cause birth defects and miscarriages so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or if you have any unexpected bruising or bleeding. Your doctor also needs to know what other medicines you are taking as there are many which interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.
03Uses
Prevention of organ rejection in transplant patients
Treatment of Rheumatoid arthritis
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aparin 50mg Tablet is to be taken with food.
05How It Works
Aparin 50mg Tablet is an immunosuppressant. It reduces the action of body’s own defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.
06What If You Miss A Dose?
If you miss a dose of Aparin 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Prevention of organ rejection in transplant patients
Aparin 50mg Tablet is an immunosuppressive agent that lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ.
In Treatment of Rheumatoid arthritis
Aparin 50mg Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Loss of appetite
Infection
Nausea
Increased bleeding tendency
Decreased white blood cell count
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aparin 50mg Tablet. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Aparin 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Aparin 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:CONSULT YOUR DOCTOR
It is not known whether Aparin 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:CAUTION
Aparin 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Aparin 50mg Tablet may be needed. Please consult your doctor.Use of Aparin 50mg Tablet is not recommended in patients with serious kidney disease.
Liver:CAUTION
Aparin 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Aparin 50mg Tablet may be needed. Please consult your doctor.Use of Aparin 50mg Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.
10Drug Tips
Your doctor has prescribed Aparin 50mg Tablet to stop the body from rejecting a transplanted organ (e.g. kidney, heart or liver).
Aparin 50mg Tablet also relieves joint pain and inflammation in rheumatoid arthritis.
You may have to take additional medications along with Aparin 50mg Tablet for better relief of symptoms.
Avoid contact with people who have cold, flu or other contagious illness. Notify your doctor if you have any signs of infection such as a fever or sore throat.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
References
Sources and references
Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.
Azathioprine. Barnstaple, Devon: Actavis UK Limited; 2018. view
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Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr . 2004;80:S189-S198. view
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Oxford Radcliffe Hospitals: NHS Trust. Azathioprine – General Information; 2012. . view
