Aplevant 0.75mg Pre-filled Pen

The dose of Aplevant 0.75mg Pre-filled Pen will depend on your condition and what other diabetes medicines you are taking. You can use it at any time of day with or without food but try to use it on the same day each week to get the most benefit. Your doctor or nurse will show you how and where to inject the medicine. Follow the instructions carefully. Do not stop taking this medicine without talking to your doctor. If you do, your blood glucose levels may increase and put you at risk of serious complications. It should be used with a proper diet and exercise to control high blood glucose. This medicine should be stored in a fridge until you need it but do not freeze it.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, and loss of appetite. It can also lead to hypoglycemia (low blood sugar level) especially if you are taking other medicines to lower blood sugar. Make sure you know how to recognize and deal with it.

Before using this medicine, talk to your doctor if you have ever had liver or kidney disease, pancreatitis, or stomach problems. Also, tell your doctor if you are taking any other medicines which may affect the way this medicine works. If you are pregnant or breastfeeding, ask your doctor if it is safe to take Aplevant 0.75mg Pre-filled Pen.

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Your doctor or nurse will guide you how to use this medicine.

Aplevant 0.75mg Pre-filled Pen is an anti-diabetic medication. It works by increasing the release of insulin from the pancreas, decreases hormones that raise blood sugar levels, slows down digestion, and reduces appetite.

If you miss a dose of Aplevant 0.75mg Pre-filled Pen, take it as soon as you remember. If the next dose is to be taken within the next 72 hours, skip the missed dose. Do not take 2 doses of Aplevant 0.75mg Pre-filled Pen within 72 hours of each other.

Aplevant 0.75mg Pre-filled Pen should be injected under the skin of your abdomen or thigh once a week. Do not administer intravenously or intramuscularly.

You can inject into the same body area each week, but try not to use the exact same spot.

Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.

Do not use Aplevant 0.75mg Pre-filled Pen if particles appear or if the solution is cloudy and/or discolored.

Aplevant 0.75mg Pre-filled Pen may cause nausea, vomiting, diarrhea, or stomach pain, which may get better with time. Eat smaller meals, limit fatty food intake and inform your doctor if it does not go away.

Q. Is Aplevant 0.75mg Pre-filled Pen an insulin?

No, Aplevant 0.75mg Pre-filled Pen is not an insulin. It is a medicine used to lower blood sugar (glucose) levels in adults with type 2 diabetes mellitus. In type 2 diabetes insulin is deficient, and the insulin that your body produces does not work as well as it should. Aplevant 0.75mg Pre-filled Pen acts on the pancreas to increase insulin release, suppress glucagon secretion, and decrease glucose production from the liver. It also slows down the emptying of the stomach.

Q. How does Aplevant 0.75mg Pre-filled Pen work for weight loss?

Aplevant 0.75mg Pre-filled Pen is used in type 2 diabetes mellitus. It improves blood sugar control and slows down digestion. This brings a feeling of fullness and satiety due to which the food intake by the patient decreases. As a result, the patient eats less which further helps in weight loss.

Q. How is Aplevant 0.75mg Pre-filled Pen administered?

Aplevant 0.75mg Pre-filled Pen is injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. It should not be injected into a muscle or vein. You can use the same area of your body each week to take the injection, but make sure that a different injection site is used within that area. Use Aplevant 0.75mg Pre-filled Pen as advised by your doctor. You can take it with or without food. If you are on insulin as well, do not mix insulin and Aplevant 0.75mg Pre-filled Pen in the same syringe. It is also recommended to check your blood sugar levels regularly.

Q. How to store Aplevant 0.75mg Pre-filled Pen?

Aplevant 0.75mg Pre-filled Pen should be refrigerated at 2°C – 8°C, but do not freeze it. Store Aplevant 0.75mg Pre-filled Pen in the original packaging to protect from light. Keep the medicine out of the reach of children. Do not use the medicine if you notice that the pen is damaged or the medicine has become cloudy/discolored or has lumps in it.

Q. Are there any potential risks of using Aplevant 0.75mg Pre-filled Pen?

Apart from the usual side effects of the medicine, Aplevant 0.75mg Pre-filled Pen has been found to cause Medullary Thyroid Carcinoma, a type of cancer of the thyroid gland. Its use may also increase the risk of inflammation of the pancreas commonly known as pancreatitis which is a serious and painful condition. Discontinue the medicine and contact your doctor immediately if you suspect any signs or symptoms of thyroid problems (lump in throat, hoarseness, and difficulty in speaking) or pancreatitis (stomach ache radiating to the back, upper abdominal pain, fever, nausea, and vomiting).

Q. What is the significance of HbA1c test?

Your doctor may ask you to get your HbA1c tested every 3 months. This test is done to see how well you have managed your blood sugar for the past 2-3 months.

Q. Can Aplevant 0.75mg Pre-filled Pen be used with other diabetes medicine?

Yes, Aplevant 0.75mg Pre-filled Pen can be used alone or in combination with other diabetes medicines only if prescribed by your doctor.

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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Loss of appetite

Stomach pain

Vomiting

Diarrhea

Nausea

Alcohol:UNSAFE

It is unsafe to consume alcohol with Aplevant 0.75mg Pre-filled Pen.

Pregnancy:CONSULT YOUR DOCTOR

Aplevant 0.75mg Pre-filled Pen may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Aplevant 0.75mg Pre-filled Pen is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:CONSULT YOUR DOCTOR

It is not known whether Aplevant 0.75mg Pre-filled Pen alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney:SAFE IF PRESCRIBED

Aplevant 0.75mg Pre-filled Pen is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Aplevant 0.75mg Pre-filled Pen may not be needed in these patients. Please consult your doctor.Use of Aplevant 0.75mg Pre-filled Pen is not recommended in patients with severe kidney disease because the information available is very limited.

Liver:SAFE IF PRESCRIBED

Aplevant 0.75mg Pre-filled Pen is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aplevant 0.75mg Pre-filled Pen may not be needed in these patients. Please consult your doctor.

Dulaglutide. Indianapolis, Indiana: Eli Lilly and Company; 2014 . view