Arthrate 10mg Tablet
Arthrate 10mg Tablet is a medicine used for the treatment of cancer in various parts of the body. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. It works by slowing the growth of abnormal cells and reducing immune system activity in autoimmune conditions.
Arthrate 10mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Arthrate 10mg Tablet is a medicine used for the treatment of cancer in various parts of the body. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. It works by slowing the growth of abnormal cells and reducing immune system activity in autoimmune conditions.
Arthrate 10mg Tablet is a medicine used for the treatment of cancer in various parts of the body. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. It works by slowing the growth of abnormal cells and reducing immune system activity in autoimmune conditions.
Arthrate 10mg Tablet may be used alone or in combination with other medicines. You should take it exactly as your doctor has advised. Taking too much of it can cause serious side effects. It may take several weeks or months for you to see or feel the benefits, but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine are ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects.
Arthrate 10mg Tablet may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Your doctor may perform several tests, such as blood tests, X-rays, and physical examinations, both before and during the treatment with this medicine to check for these problems.
Before taking it, tell your doctor if you have problems related to the stomach, liver, or kidneys, or are taking any medicines to treat infections. Many other medicines can affect or be affected by this medicine, so let your doctor know about all your medications. This medicine is not recommended during pregnancy or while breastfeeding, as it may harm the baby. You should avoid consuming alcohol while taking this medicine, as it may increase your risk of liver damage.
03Uses
Treatment of Cancer
Treatment of Rheumatoid arthritis
Treatment of Psoriasis
Treatment of Crohn’s disease
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Arthrate 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
05How It Works
Arthrate 10mg Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division, and leads to anti-inflammatory actions. Arthrate 10mg Tablet kills cancer cells by preventing them from making DNA. Arthrate 10mg Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Arthrate 10mg Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body’s cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis or damage to the intestine in Crohn’s disease.
06What If You Miss A Dose?
Q: What if you forget to take Arthrate Tablet?
A: If you miss a dose of Arthrate 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Treatment of Cancer
Arthrate 10mg Tablet works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers, such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in the breast, lung, bladder, head, and neck, as well as cervical, ovarian, and testicular cancer. It may be given alone or in combination with other medicines.
08Side Effects
Nausea
Abdominal pain
Ulcerative stomatitis
Decreased blood cells (red cells, white cells, and platelets)
09Safety Information
Alcohol:UNSAFE
It is unsafe to consume alcohol with Arthrate 10mg Tablet.
Pregnancy:UNSAFE
Arthrate 10mg Tablet is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:UNSAFE
Arthrate 10mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:CONSULT YOUR DOCTOR
It is not known whether Arthrate 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:CAUTION
Arthrate 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Arthrate 10mg Tablet may be needed. Please consult your doctor.Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver:CAUTION
Arthrate 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Arthrate 10mg Tablet may be needed. Please consult your doctor.
10Drug Tips
Drink plenty of liquids to stay hydrated while taking this medication.
Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine.
Arthrate 10mg Tablet may take from weeks to months for Arthrate 10mg Tablet to work. Keep taking the medication as prescribed.
Your doctor may get regular blood tests done to monitor your kidney function, liver function, and the level of blood cells in your blood.
Avoid drinking alcohol while taking this medicine, as it may increase the risk of side effects.
References
Sources and references
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. [Accessed 19 Apr. 2023] (online) Available from: View
Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. [Accessed 19 Apr. 2023] (online) Available from: View
Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 [Accessed 19 Apr. 2023] (online) Available from: View
Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. [Accessed 19 Apr. 2023] (online) Available from: View
Crohn’s & Colitis, UK. Methotrexate [Information Sheet]. [Accessed 19 Apr. 2023] (online) Available from: View
Methotrexate [Prescribing Information]. Berkeley Heights, NJ: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 26 Feb. 2025] (online) Available from: View
