
Basugine 100IU/ml Injection
Basugine 100IU/ml Injection is a long-acting type of insulin used to treat types 1 and 2 diabetes mellitus in both adults and children. It provides a steady level of insulin in the body for an entire day and helps control blood sugar levels. This helps to prevent complications of diabetes.
Basic Info
Description
Basugine 100IU/ml Injection can be prescribed alone or along with fast-acting insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the maximum benefit. If you stop taking it, your blood sugar levels may rise very high which may put you at risk of serious complications. It is only a part of the treatment program that should also include a healthy diet, regular exercise and weight reduction as advised by your doctor.
The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it is important to inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include allergy at the injection site like redness, swelling, or hard lumps (lipohypertrophy). Some people gain weight while taking insulin.
Do not use this medicine when you have low blood sugar levels. Before starting the treatment, inform your doctor if you have ever had kidney, liver or heart problems. Pregnant or breastfeeding women should consult their doctor before using it.
Uses
Diabetes Mellitus (Type 1 and Type 2)
How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
MOA
Basugine 100IU/ml Injection is a long-acting insulin that provides consistent, all-day sugar control. It works like your body’s natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
What If
If you miss a dose of Basugine 100IU/ml Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Drug Tips
Basugine 100IU/ml Injection is injected under the skin. It needs to be injected once daily, at the same time every day.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
Hypoglycemia (low blood sugar level) is a common side effect. Hence, regular monitoring of blood sugar levels is required while taking this medicine.
Always carry some high sugar food such as sugar candy or glucose candy, fruit juice and glucose/glucon-D with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremors, weakness, and anxiety.
Opened vials/cartridge stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Do not use if the preparation is no longer clear and colorless, or if it contains particles.
Faqs
Q. What kind of insulin is Basugine 100IU/ml Injection?
Basugine 100IU/ml Injection is a man-made insulin, which is very similar to human insulin. It has a long and steady (constant) effect on the blood sugar levels and the action lasts for an entire day. This makes it suitable to be used once daily. It is used to treat type 2 diabetes mellitus in adults and type 1 diabetes mellitus in adults and children.
Q. How is Basugine 100IU/ml Injection administered?
Basugine 100IU/ml Injection is injected just below the skin (subcutaneously). Your doctor will train you on the correct method and the areas (abdomen or stomach, thighs, arms, hips or buttocks) where you should inject it. It is advised that the site of injection should be changed within the chosen area of skin, for every dose. For example, if you have been advised to inject it into the skin of your stomach, avoid puncturing the same point on your stomach every day. Rather, inject the needle at a site that is slightly away, say around 1cm, from the previous injection. You can also consider switching sides while injecting, like choosing the right side on one day and the left side on the next day. This way, you can reduce the complications associated with repeated injections in the same site such as thickening of the fat tissue below the skin known as lipodystrophy, irritation, pain etc. After one to two weeks, you should move to another area of your body (eg. from the stomach to the arms or thighs) as advised by your doctor. Consult your doctor if you face any problems while injecting Basugine 100IU/ml Injection.
Q. Can I take Basugine 100IU/ml Injection twice a day?
Basugine 100IU/ml Injection is long-acting and is usually prescribed to be taken once a day. It can be taken at any time of the day, but try to take it at the same time each day.
Q. What will happen if I accidentally inject more than the prescribed dose of Basugine 100IU/ml Injection?
If you have accidentally taken more than the prescribed dose of Basugine 100IU/ml Injection, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugary candy, fruit juice, and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and the patient should be rushed to an emergency.
Q. How should Basugine 100IU/ml Injection be stored?
Keep this medication out of the reach of children in the container it came in. Store unopened vials and pens in the refrigerator, but do not freeze them. An unopened, Basugine 100IU/ml Injection can be stored in the refrigerator until the date shown on the company’s label. Moreover, never use Basugine 100IU/ml Injection that has been frozen or defrosted. If a refrigerator is unavailable, the vials can be stored at room temperature and away from direct sunlight and extreme heat. It should appear as a clear, colorless solution that is free from any particles.
Q. In what circumstances will the dose of Basugine 100IU/ml Injection need to be changed?
You should consult your doctor about the scenarios where you may need to adjust your insulin dose. For example, in case you are ill, you should monitor your blood sugar levels more closely. You must tell your doctor about all the medicines that you are taking because many medicines can affect the way insulin acts and you may need dose modification. Your eating habits may also affect your dose, for example, if you eat less someday, skip a meal or eat more than what you usually eat. Your blood sugar level may alter depending upon your exercise regime, alcohol consumption or stress. Pregnant and breastfeeding mothers should consult their doctor before taking Basugine 100IU/ml Injection as they may need to change their dose.
Q. What are the serious side effects of Basugine 100IU/ml Injection?
Serious side effects are rare with Basugine 100IU/ml Injection. Sometimes, severe allergic reaction may be seen with it. This can lead to rash, hives, itching all over the body, trouble breathing (wheezing), fast heart rate, and low blood pressure. Get medical help right away if you develop any of these symptoms. Other side effects include severe hypoglycemia (low blood sugar levels), that can cause dizziness, sweating, anxiety, confusion, headache, blurred vision, slurred speech, shakiness, fast heartbeat, seizure (fit), and unconsciousness. Taking certain medicines such as TZDs (thiazolidinediones) may cause heart failure in some people, even if they have never had any heart problems before. Some people may also notice sudden weight gain and swelling (edema) of ankles or feet. Consult your doctor immediately if you notice any of these side effects.
Benefits
In Diabetes Mellitus (Type 1 and Type 2)
Basugine 100IU/ml Injection is a man-made form of insulin that helps to control high blood glucose (sugar) levels. It replaces the insulin that is normally produced in the body. This helps the glucose get into your cells so your body can use it for energy. Lowering of blood sugar level helps reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. You will need to learn exactly how, where, and when to inject this insulin for it to be most effective. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Lipodystrophy (skin thickening or pits at the injection site)
Injection site allergic reaction
Hypoglycemia (low blood glucose level)
Safety Profile
Alcohol:UNSAFE
It is unsafe to consume alcohol with Basugine 100IU/ml Injection.
Pregnancy:CONSULT YOUR DOCTOR
Basugine 100IU/ml Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Basugine 100IU/ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving:CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney:CAUTION
Basugine 100IU/ml Injection should be used with caution in patients with kidney disease. Dose adjustment of Basugine 100IU/ml Injection may be needed. Please consult your doctor.Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver:CAUTION
Basugine 100IU/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Basugine 100IU/ml Injection may be needed. Please consult your doctor.Regular monitoring of glucose levels is recommended for dose adjustment.
Refferences
Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1251-52.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 734.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 720.
Insulin glargine. Sesto Fiorentino, Italy: Eli Lilly Italia S.p.A.; 2018. view
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr . 2004;80:S189-98. view
Dr. Pritpal Singh Saini
MBBS, DNB (Ortho). Specialist in Arthroscopy, Joint Replacement & Trauma Surgery. Founder of MedbeW.
Medical Disclaimer: This content is for educational use only and not a substitute for professional medical advice. Consult a doctor before starting any treatment.
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