Bavencio Injection
Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.
Bavencio Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.
Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.
Bavencio Injection is given as an injection by a healthcare professional. For it to be effective, complete the course of the medicine and do not discontinue even if you get better until the course is completed.
Some common side effects of this medicine include fatigue, nausea, diarrhea, decreased appetite, and muscle pain amongst others. These are usually mild and go away with time. However, if they persist or get worse, let the doctor know.
Before receiving the medicine, you should let your doctor if you have ever had an allergic reaction to any medicine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this medicine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this medicine.
03Uses
Treatment of Urinary bladder cancer
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Bavencio Injection is a type of immunotherapy. It activates the body’s immune system to fight cancer cells. Avelumab targets and blocks a protein (PD-L1) found on the surface of certain immune cells. Blocking PD-L1 activates the immune cells to find and kill cancer cells.
06What If You Miss A Dose?
Q: What if you forget to take Bavencio Injection?
A: If you miss a dose of Bavencio Injection, consult your doctor.
07Benefits
In Treatment of Urinary bladder cancer
Bavencio Injection helps to treat urinary bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse and should not be self-administered.
08Side Effects
Fatigue
Musculoskeletal (bone, muscle or joint) pain
Diarrhea
Nausea
Infusion site reaction
Rash
Decreased appetite
Peripheral edema
Urinary tract infection
High blood pressure
Mucositis
Hand-foot syndrome
Voice change
Decreased level of thyroid hormones
Liver toxicity
Coughing up blood
Breathlessness
Abdominal pain
Headache
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bavencio Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Bavencio Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CAUTION
Bavencio Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving:SAFE
Bavencio Injection does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Bavencio Injection is safe to use in patients with kidney disease. No dose adjustment of Bavencio Injection is recommended.
Liver:SAFE IF PRESCRIBED
Bavencio Injection is safe to use in patients with liver disease. No dose adjustment of Bavencio Injection is recommended.
10Drug Tips
Do not receive any immunization or vaccination without your doctor’s approval while taking Bavencio Injection.
You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your health care provider.
Inform your doctor immediately if you notice signs or symptoms of skin rash, itchy skin, a rash with tiny spots and bumps, reddening of the skin.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Use contraceptives, and do not conceive a child (get pregnant) while taking Bavencio Injection. Barrier methods of contraception, such as condoms, are recommended.
Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
Do not drive or use machines after you have received Bavencio Injection since you might feel tired or dizzy.
References
Sources and references
Bavencio (Avelumab) [Product Information]; 2021. [Accessed 16 Nov. 2022] (online) Available from: View
Avelumab [Prescribing Information]. Rockland, MA: : EMD Serono, Inc.; 2022. [Accessed 16 Nov. 2022] (online) Available from: View
Avelumab [Summary of Product Characteristics]. Modugno, Italy: Merck Serono S.p.A.; 2020. [Accessed 16 Nov. 2022] (online) Available from: View
