Bderlo 150mg Tablet
Bderlo 150mg Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.
Bderlo 150mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Bderlo 150mg Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.
Bderlo 150mg Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.
Bderlo 150mg Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.
03Uses
Pancreatic cancer
Non-small cell lung cancer
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bderlo 150mg Tablet is to be taken empty stomach.
05How It Works
Bderlo 150mg Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.
06What If You Miss A Dose?
Q: What if you forget to take Bderlo Tablet?
A: If you miss a dose of Bderlo 150mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
07Benefits
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Bderlo 150mg Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
08Side Effects
Abdominal pain
Bone pain
Breathlessness
Constipation
Cough
Diarrhea
Fatigue
Fever
Infection
Muscle pain
Nausea
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weight loss
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bderlo 150mg Tablet. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Bderlo 150mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Bderlo 150mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:CONSULT YOUR DOCTOR
It is not known whether Bderlo 150mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:SAFE IF PRESCRIBED
Bderlo 150mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Bderlo 150mg Tablet is recommended.Use of this medicine is not advised in patients with severe kidney disease.
Liver:CAUTION
Bderlo 150mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bderlo 150mg Tablet may be needed. Please consult your doctor.
10Drug Tips
Bderlo 150mg Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
It should be taken 1 hour before or 2 hours after the meal.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective clothing while going out.
It is advisable to avoid smoking while taking this medicine, as it makes the drug ineffective and requires dose adjustment.
Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
References
Sources and references
Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1735-36.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 489-90.
Erlotinib. Seymour, Indiana: Schwarz Pharma Manufacturing; 2014 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Erlotinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: View
Erlotinib [Prescribing Information]. Seymour, IN: Schwarz Pharma Manufacturing; 2010. [Accessed 25 Jul. 2024] (online) Available from: View
