Bionase 5000IU Injection
Bionase 5000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
Bionase 5000IU Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Bionase 5000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
Bionase 5000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
Bionase 5000IU Injection is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effect of this medicine includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar levels, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy, and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.This medicine may lower your body’s resistance and increase susceptibility to infections. Infections can sometimes be life-threatening. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
03Uses
Blood cancer (Acute lymphocytic leukemia)
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Asparaginase belongs to class of medications called antineoplastic agents. Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells.
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06Benefits
In Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Bionase 5000IU Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
07Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Hives
Increased glucose level in blood
Low albumin level in blood
Flushing (sense of warmth in the face, ears, neck and trunk)
Decreased blood pressure
Diarrhea
Increased liver enzymes
Fatigue
Nausea
Edema (swelling)
Angioedema (swelling of deeper layers of skin)
Vomiting
Rash
Breathlessness
08Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bionase 5000IU Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Bionase 5000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Bionase 5000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:SAFE
Bionase 5000IU Injection does not usually affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Bionase 5000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bionase 5000IU Injection may not be needed in these patients. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Bionase 5000IU Injection in patients with liver disease. Please consult your doctor.However, regular monitoring of liver function tests is advised while you are taking this medicine.
09Drug Tips
Bionase 5000IU Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.
It is advisable to drink plenty of fluids and stay hydrated while taking this medication.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, liver function and kidney function during treatment.
It can cause an increase in blood sugar levels. Hence, monitor your blood sugar level regularly.
References
Sources and references
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1720-21.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 956.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 88.
Asparaginase. Wedel, Germany: medac GmbH; 2016 . view
Drugs.com. Asparaginase erwinia chrysanthemi Pregnancy and Breastfeeding Warnings. view
Central Drugs Standard Control Organisation . view
