Biopanib 400mg Tablet
Biopanib 400mg Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.
Biopanib 400mg Tablet
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Biopanib 400mg Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.
Biopanib 400mg Tablet is a protein kinase inhibitor used in the treatment of kidney cancer and soft tissue sarcoma.
Biopanib 400mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Diarrhea and high blood pressure are the most common side effects of this medicine. Doctor may advise for regular monitoring of your blood pressure while on treatment. Drink plenty of fluids to overcome diarrhea or consult with your doctor if it bothers you. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you experience fever, flu-like symptoms and shortness of breath.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Kidney cancer
Soft tissue sarcoma
04How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Biopanib 400mg Tablet is to be taken empty stomach.
05How It Works
Biopanib 400mg Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.
06What If You Miss A Dose?
Q: What if you forget to take this medicine?
A:
07Side Effects
Headache
Nausea
Vomiting
Musculoskeletal (bone, muscle or joint) pain
Fatigue
Change in color of hair
Diarrhea
High blood pressure
Decreased appetite
Weight loss
Taste change
Abnormal skin pigmentation
Hair discoloration
Tumor pain
Breathlessness
08Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Biopanib 400mg Tablet. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Biopanib 400mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Biopanib 400mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Biopanib 400mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:SAFE IF PRESCRIBED
Biopanib 400mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Biopanib 400mg Tablet is recommended.
Liver:CAUTION
Biopanib 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Biopanib 400mg Tablet may be needed. Please consult your doctor.Use of Biopanib 400mg Tablet is not advised in patients with moderate to severe liver disease.
References
Sources and references
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1072-73.
Pazopanib. Research Triangle Park, North Carolina: GlaxoSmithKline; 2009 [revised Apr. 2012]. [Accessed 24 Jan. 2019] (online) Available from: View
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from: View
