Bortirel 3.5mg Injection
Bortirel 3.5mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
Bortirel 3.5mg Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Bortirel 3.5mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
Bortirel 3.5mg Injection is used in the treatment of multiple myeloma and mantle-cell lymphoma. It shows its working by stopping or slowing down the growth of cancer cells.
Bortirel 3.5mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.Before taking
Bortirel 3.5mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem. It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Multiple myeloma
Mantle-cell lymphoma
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Bortirel 3.5mg Injection is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.
06What If You Miss A Dose?
If you miss a dose of Bortirel 3.5mg Injection, please consult your doctor.
07Benefits
In Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Bortirel 3.5mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
In Mantle-cell lymphoma
Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin’s lymphoma. White blood cells are those cells that help us to fight infections. Bortirel 3.5mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.show moreshow less
08Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Constipation
Decreased white blood cell count (neutrophils)
Decreased appetite
Diarrhea
Anemia (low number of red blood cells)
Fever
Loss of appetite
Vomiting
Nausea
Psychiatric disturbances
Peripheral neuropathy (tingling and numbness of feet and hand)
Fatigue
Low blood platelets
09Safety Information
Alcohol:UNSAFE
Bortirel 3.5mg Injection may cause excessive drowsiness with alcohol.
Pregnancy:CONSULT YOUR DOCTOR
Bortirel 3.5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Bortirel 3.5mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Bortirel 3.5mg Injection may cause side effects which could affect your ability to drive.Bortirel 3.5mg Injection might cause tiredness, dizziness, fainting, or blurred vision which may affect your ability to drive.
Kidney:CAUTION
Bortirel 3.5mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Bortirel 3.5mg Injection may be needed. Please consult your doctor.Limited information is available on the use of Bortirel 3.5mg Injection in these patients.
Liver:CAUTION
Bortirel 3.5mg Injection should be used with caution in patients with liver disease. Dose adjustment of Bortirel 3.5mg Injection may be needed. Please consult your doctor.
10Drug Tips
Bortirel 3.5mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet.
References
Sources and references
Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1742-43.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 958.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 153-54.
Central Drugs Standard Control Organisation . view
Bortezomib. Beerse Belgium: Janssen Pharmaceutica NV; view
