Bosewise GM 2mg/500mg/0.2mg Tablet

Bosewise GM 2mg/500mg/0.2mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Take Bosewise GM 2mg/500mg/0.2mg Tablet with or immediately before meals. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you, and this may change from time to time depending on how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

Common side effects of Bosewise GM 2mg/500mg/0.2mg Tablet are nausea, vomiting, abdominal pain, and loss of appetite. Make sure you recognize the signs of low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it’s important to have regular meals and always carry a fast-acting source of glucose, such as sugary food or fruit juice, with you.

Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take Bosewise GM 2mg/500mg/0.2mg Tablet if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, as it may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly, and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Treatment of Type 2 diabetes mellitus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bosewise GM 2mg/500mg/0.2mg Tablet is to be taken with food.

Bosewise GM 2mg/500mg/0.2mg Tablet is a combination of three antidiabetic medicines: glimepiride, metformin, and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that lowers glucose production in the liver, delays glucose absorption from the intestines, and increases the body’s sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor that prevents the breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.

Q: What if you forget to take Bosewise GM Tablet?
A: If you miss a dose of Bosewise GM 2mg/500mg/0.2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Bosewise GM 2mg/500mg/0.2mg Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines or alcohol, or if you delay or miss a meal. Carry a sugar source with you for immediate relief.

Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Individuals with severe renal or hepatic impairment should not take Bosewise GM 2mg/500mg/0.2mg Tablet.

This medicine works best when used along with proper diet and exercise.

Q. What is Bosewise GM 2mg/500mg/0.2mg Tablet?

Bosewise GM 2mg/500mg/0.2mg Tablet is a combination of medicines used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with a proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering glucose production in the liver and improving insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor that lowers the postprandial (after meals) glucose levels in the body. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Bosewise GM 2mg/500mg/0.2mg Tablet?

The use of Bosewise GM 2mg/500mg/0.2mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, flatulence, stomach pain, headache, skin rash and respiratory tract infection.

Q. Are there any specific conditions in which Bosewise GM 2mg/500mg/0.2mg Tablet should not be taken?

The use of Bosewise GM 2mg/500mg/0.2mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also avoided in patients with moderate to severe kidney disease and in patients with inflammatory bowel disease, colonic ulcerations and underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to drink alcohol while I am also taking Bosewise GM 2mg/500mg/0.2mg Tablet?

No, it is not safe to take Bosewise GM 2mg/500mg/0.2mg Tablet with alcohol. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. Can the use of Bosewise GM 2mg/500mg/0.2mg Tablet cause hypoglycemia?

Yes, the use of Bosewise GM 2mg/500mg/0.2mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Q. What are the instructions for the storage and disposal of Bosewise GM 2mg/500mg/0.2mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

In Treatment of Type 2 diabetes mellitus

Bosewise GM 2mg/500mg/0.2mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps to slow down the breaking down of food in our intestine to simple glucose (sugar), thereby decreasing the rise in blood glucose levels after meals. It also helps get rid of extra glucose from your body through urine. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level, you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems and loss of limbs. Bosewise GM 2mg/500mg/0.2mg Tablet will reduce the risk of dying from cardiovascular disease if you have type 2 diabetes and already have cardiovascular disease. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed because it is protecting your future health.

Nausea

Diarrhea

Abdominal pain

Hypoglycemia (low blood glucose level)

Loss of appetite

Alcohol:UNSAFE

It is unsafe to consume alcohol with Bosewise GM 2mg/500mg/0.2mg Tablet.

Pregnancy:CONSULT YOUR DOCTOR

Bosewise GM 2mg/500mg/0.2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding:CONSULT YOUR DOCTOR

Bosewise GM 2mg/500mg/0.2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney:UNSAFE

Bosewise GM 2mg/500mg/0.2mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.Use of Bosewise GM 2mg/500mg/0.2mg Tablet is, however, not recommended in patients with severe kidney disease.

Liver:CAUTION

Bosewise GM 2mg/500mg/0.2mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bosewise GM 2mg/500mg/0.2mg Tablet may be needed. Please consult your doctor.Bosewise GM 2mg/500mg/0.2mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

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Dabhi AS, Bhatt NR, Shah MJ. Voglibose: An Alpha Glucosidase Inhibitor. J Clin Diagn Res. 2013;7(12):3023-7. [Accessed 08 Apr. 2019] (online) Available from: View
Glimepiride+Metformin+Voglibose [Product Monograph]. Punjab, India: Centaur Pharmaceuticals Pvt. Ltd.; 2018. [Accessed 25 Oct. 2021] (online) Available from: View
Metformin Hydrochloride (Prolonged Release), Voglibose & Glimepiride [Patient Information Sheet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2015. [Accessed 28th Sept. 2023] (online) Available from: View