Citafine 1400mg Injection
Citafine 1400mg Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.
Citafine 1400mg Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Citafine 1400mg Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.
Citafine 1400mg Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.
Citafine 1400mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include nausea, vomiting, loss of appetite, hair loss and low blood platelets. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Non-small cell lung cancer
Breast cancer
Pancreatic cancer
Urinary bladder cancer
Ovarian cancer
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Citafine 1400mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.
06Benefits
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Citafine 1400mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Breast cancer
Citafine 1400mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Citafine 1400mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Citafine 1400mg Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
In Urinary bladder cancer
Urinary bladder cancer is the type of cancer that develops in the bladder, usually in older adults. The most common symptom of this cancer is blood in the urine. Citafine 1400mg Injection is used in combination with other medicines such as cisplatin to treat urinary bladder cancer that has advanced to later stages or even spread to other regions of the body (metastasized). It is a highly effective medicine and also prevents the cancer from returning. However, you must discuss the risks and benefits of this medicine before starting your treatment.
In Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Citafine 1400mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about ways that can help you avoid these side effects.show moreshow less
07Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Protein in urine
Skin rash
Blood in urine
Flu-like symptoms
Anemia (low number of red blood cells)
Increased liver enzymes
Decreased white blood cell count
Breathlessness
Allergic reaction
Low blood platelets
Hair loss
Loss of appetite
Vomiting
Nausea
08Safety Information
Alcohol:UNSAFE
Citafine 1400mg Injection may cause excessive drowsiness with alcohol.
Pregnancy:CONSULT YOUR DOCTOR
Citafine 1400mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding:UNSAFE
Citafine 1400mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving:UNSAFE
Citafine 1400mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney:CONSULT YOUR DOCTOR
There is limited information available on the use of Citafine 1400mg Injection in patients with kidney disease. Please consult your doctor.Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Citafine 1400mg Injection in patients with liver disease. Please consult your doctor.
09Drug Tips
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
References
Sources and references
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1700-701.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 947-48.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 617-18.
Gemcitabine hydrochloride. Hayes, UK: RanbaxyLimited a Sun Pharmaceutical Company; 2013 view
Drug.com. Gemcitabine Pregnancy and Breastfeeding Warnings. view
Central Drugs Standard Control Organisation . view
