Conimab 500mg Injection
Conimab 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.
Conimab 500mg Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Conimab 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.
Conimab 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.
Conimab 500mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.
Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Non-Hodgkin lymphoma (NHL)
Blood cancer (Chronic lymphocytic leukemia)
Rheumatoid arthritis
Granulomatosis with polyangiitis
Microscopic polyangiitis
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Conimab 500mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
06What If You Miss A Dose?
Q: What if you forget to take Conimab Injection?
A: If you miss a dose of Conimab 500mg Injection, please consult your doctor.n
07Benefits
In Granulomatosis with polyangiitis
Granulomatosis with polyangiitis is a condition that causes inflammation of the blood vessels of the ears, nose, throat, lungs, and kidneys. In this condition, the blood flow to these areas may be reduced and it can lead to their damage. Conimab 500mg Injection helps reduce inflammation, pain and swelling and prevents further damage. This improves your quality of life.
08Side Effects
Headache
Weakness
Infection
Chills
Decreased white blood cell count (neutrophils)
Fever
Infusion site reaction
Lymphopenia
Abdominal pain
Back pain
09Safety Information
Alcohol:CAUTION
Caution is advised when consuming alcohol with Conimab 500mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Conimab 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:SAFE IF PRESCRIBED
Conimab 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving:CONSULT YOUR DOCTOR
It is not known whether Conimab 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:SAFE IF PRESCRIBED
Conimab 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Conimab 500mg Injection may not be needed in these patients. Please consult your doctor.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Conimab 500mg Injection in patients with liver disease. Please consult your doctor.Use of Conimab 500mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.
10Drug Tips
It is given as a drip (intravenous infusion) by your doctor or nurse.
You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Inform your doctor if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.
References
Sources and references
Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1745-48.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1225-27.
Rituximab. Garden City, Hertfordshire: Roche Products Limited; 1998 [revised 18 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rituximab. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from: View
