Cytalon 1000 Injection

Cytalon 1000 Injection is used to treat some kinds of cancers of blood. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Cytalon 1000 Injection is given as an injection into the vein or under skin by the healthcare professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include rash, skin ulcer, nausea, vomiting, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections or bleeding. Inform your doctor if you notice chills, unusual bleeding or bruising and black and tarry stools. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Blood cancer

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Cytalon 1000 Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Q: What if you forget to take this medicine?
A:

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.

Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Q. Is Cytalon 1000 Injection a vesicant?

No. Cytalon 1000 Injection is not a vesicant (irritant) but should be handled with care.

Q. Is Cytalon 1000 Injection ototoxic?

No. Ototoxicity is not reported with use of Cytalon 1000 Injection. However, please consult your doctor if you experience such a side effect.

Q. Is Cytalon 1000 Injection cytotoxic?

Yes. Cytalon 1000 Injection is a cytotoxic drug.

Q. Does Cytalon 1000 Injection cause hair loss?

Yes. Cytalon 1000 Injection may cause hair loss.

Q. How does Cytalon 1000 Injection prevent DNA replication?

Cytalon 1000 Injection prevents deoxyribonucleic acid (DNA) replication by inhibiting the synthesis of DNA.

In Blood cancer

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Cytalon 1000 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Rash

Skin ulcer

Nausea

Vomiting

Hair loss

Abdominal pain

Anal ulcers

Anemia (low number of red blood cells)

Decreased white blood cell count

Fever

Infection

Abnormal liver function

Low blood platelets

Mouth ulcer

Pneumonia

Sepsis

Mouth sore

Stomatitis (Inflammation of the mouth)

Alcohol:CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cytalon 1000 Injection. Please consult your doctor.

Pregnancy:CONSULT YOUR DOCTOR

Cytalon 1000 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding:UNSAFE

Cytalon 1000 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving:UNSAFE

Cytalon 1000 Injection may cause side effects which could affect your ability to drive.

Kidney:SAFE IF PRESCRIBED

Cytalon 1000 Injection is safe to use in patients with kidney disease. No dose adjustment of Cytalon 1000 Injection is recommended.However, talk to your doctor if you have any underlying kidney disease.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Cytalon 1000 Injection in patients with liver disease. Please consult your doctor.Because of the limited information, a cautious use of Cytalon 1000 Injection is recommended in patients with liver disease.

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1698-700.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 947.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 343-44.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: View