Daronem 500mg Injection
Daronem 500mg Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.
Daronem 500mg Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Daronem 500mg Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.
Daronem 500mg Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.
Daronem 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
03Uses
Malignant melanoma
Hodgkin’s disease
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Daronem 500mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
06What If You Miss A Dose?
Q: What if you forget to take Daronem Injection?
A: If you miss a dose of Daronem 500mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
07Benefits
In Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Daronem 500mg Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.
08Side Effects
Nausea
Vomiting
Injection site pain
Decreased white blood cell count
Loss of appetite
09Safety Information
Alcohol:CAUTION
Caution is advised when consuming alcohol with Daronem 500mg Injection. Please consult your doctor.
Pregnancy:CONSULT YOUR DOCTOR
Daronem 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding:CONSULT YOUR DOCTOR
Daronem 500mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:UNSAFE
Daronem 500mg Injection may cause side effects which could affect your ability to drive.Daronem 500mg Injection may influence the ability to drive because of its central nervous system side effects.
Kidney:CAUTION
Daronem 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Daronem 500mg Injection may be needed. Please consult your doctor.
Liver:CAUTION
Daronem 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Daronem 500mg Injection may be needed. Please consult your doctor.
10Drug Tips
Daronem 500mg Injection is given as an injection into veins under the supervision of a doctor.
References
Sources and references
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 [revised Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from: View
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dacarbazine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from: View
