Dinost 0.5mg Gel
Dinost 0.5mg Gel is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals. The dose and how often you take it depends on what you are taking it for. You might be asked to lie down for at least 30 minutes after medicine application.
Dinost 0.5mg Gel
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Dinost 0.5mg Gel is a medicine used to induce labor in women, who are ready to deliver a full term baby. It works by softening and widening the cervix (lower end of the uterus) and helps the baby to pass through easily.
Dinost 0.5mg Gel is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals. The dose and how often you take it depends on what you are taking it for. You might be asked to lie down for at least 30 minutes after medicine application.
The most common side effects of this medicine include vomiting, diarrhea, back pain, and flushing of the skin. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a heart attack, or have asthma or have high or low blood pressure. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You may be checked for contraction timely by your doctor while on treatment with this medicine.
03Uses
Induction of labour
04How To Use
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying
05How It Works
Dinost 0.5mg Gel is similar to a natural substance (E2 prostaglandin) which is released in your body when labour starts. It works by opening the part of the birth canal (cervix) and causing the uterus to contract, to allow the baby through.
06Benefits
In Induction of labour
Dinost 0.5mg Gel contains a natural substance (prostaglandin) called Dinoprostone, that your body makes in preparation for labour or delivery of a full term baby. It softens and widens the opening of the womb and increases contractions of the uterus. This helps the baby to come out of the mother’s womb with ease and prevents any complications involved with childbirth.
07Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Flushing of skin
Increased uterine contractions
Fetal distress
Back pain
Diarrhea
Vomiting
08Safety Information
Alcohol:
No interaction found/established
Pregnancy:SAFE IF PRESCRIBED
Dinost 0.5mg Gel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding:CONSULT YOUR DOCTOR
Dinost 0.5mg Gel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving:
No interaction found/established
Kidney:
No interaction found/established
Liver:
No interaction found/established
09Drug Tips
Dinost 0.5mg Gel helps induce labour in pregnant women.
It is only used in a hospital or clinic by your doctor.
Your doctor may ask you to lie down for at least 30 minutes to keep the medication in place.
A second dose of medicine may be given if contractions are not strong enough.
You may be monitored closely after administration to make sure that the contractions do not become too strong and no distress comes to the baby.
Inform your doctor if you have heart, kidney, lung or liver disease or if you have a history of asthma.
References
Sources and references
Schimmer BP, Parker KL. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1850.
Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 325.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 413-14.
Dinoprostone. New York, New York: Pfizer; 2017. view
Dinoprostone. East Kilbride, Scotland: Ferring Controlled Therapeutics Ltd. ; 2017. view
Drugs.com. Dinoprostone. view
Central Drugs Standard Control Organisation . view
