Dogest-Depot 500mg Injection
Dogest-Depot 500mg Injection provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.
Dogest-Depot 500mg Injection
Basic Information
Important information about this medicine
About This Medicine
General information about this product
Dogest-Depot 500mg Injection provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.
Dogest-Depot 500mg Injection provides progesterone, which is a natural hormone essential for reproductive health. It is used to support pregnancy in female infertility and as part of hormone replacement therapy. It helps regulate the menstrual cycle, prepares the uterus for pregnancy, and balances hormones.
You should use Dogest-Depot 500mg Injection as your doctor has advised. It is given as an injection by a healthcare professional. Do not exceed the prescribed dose or use it for longer than recommended. Your doctor may advise you to continue receiving this injection for a certain period after pregnancy is confirmed.
The most common side effects include headache, back pain, dizziness, weight gain, vaginal discharge, stomach cramps, pain or swelling in your abdomen, and feeling sick. You may also feel bloated, less interested in sex, and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally, people get a severe allergic reaction that needs urgent medical attention.
Dogest-Depot 500mg Injection may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina, or liver disease. You may be monitored more carefully if you have liver, kidney, or heart problems, or have diabetes or asthma.
Let your doctor know your medical history. Check with your doctor about all other medicines that may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. In general, alcohol is not recommended while taking this medicine.
03Uses
Female infertility
Hormone replacement therapy
04How To Use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
05How It Works
Dogest-Depot 500mg Injection works by preparing the uterus for pregnancy and maintaining a healthy environment for fetal development. It thickens the uterine lining to support implantation and prevents contractions that could lead to early pregnancy loss. Additionally, it helps regulate the menstrual cycle and balances other reproductive hormones. In hormone therapy, it supports overall hormonal stability and helps manage symptoms related to hormonal imbalances.
06What If You Miss A Dose?
Q: What if you forget to take Dogest-Depot Injection?
A: If you miss a dose of Dogest-Depot 500mg Injection, consult the doctor.
07Benefits
In Female infertility
Dogest-Depot 500mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
08Side Effects
Nervousness
Decreased libido
Anorgasmia (decreased orgasm)
Depression
Insomnia (difficulty in sleeping)
Headache
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
Abdominal pain
Abdominal discomfort
Abdominal distension
Nausea
Back pain
Leg cramps
Irregular uterine bleeding
Vaginal discharge
Breast pain
Breast tenderness
Pain during periods
Pelvic pain
Vaginal inflammation
Edema (swelling)
Weakness
Fatigue
Change in body weight
09Safety Information
Alcohol:CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dogest-Depot 500mg Injection. Please consult your doctor.
Pregnancy:UNSAFE
Dogest-Depot 500mg Injection is highly unsafe to use during pregnancy. Seek your doctor’s advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding:CONSULT YOUR DOCTOR
Information regarding the use of Dogest-Depot 500mg Injection during breastfeeding is not available. Please consult your doctor.
Driving:UNSAFE
Dogest-Depot 500mg Injection may cause side effects which could affect your ability to drive.
Kidney:SAFE IF PRESCRIBED
Dogest-Depot 500mg Injection is safe to use in patients with kidney disease. No dose adjustment of Dogest-Depot 500mg Injection is recommended.
Liver:CONSULT YOUR DOCTOR
There is limited information available on the use of Dogest-Depot 500mg Injection in patients with liver disease. Please consult your doctor.Use of Dogest-Depot 500mg Injection is however not recommended in patients with severe liver disease.
10Drug Tips
Do not self-administer unless advised. Only inject at home if your doctor has trained you properly.
Let your doctor know if you have any history of blood clots, breast cancer, or liver issues before starting treatment.
Your doctor may schedule hormone level tests or scans to monitor your response to treatment. Make sure to attend all scheduled appointments for best results.
References
Sources and references
Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Progesterone. Lodi, Italy: IBSA Farmaceutici Italia Srl; 2013. [Accessed 21 Jun. 2019] (online) Available from: View
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from: View
Progesterone [Product Description]. Corona, CA: Watson Laboratories, Inc.; 2007. [Accessed 28 Mar. 2023] (online) Available from: View
Medroxyprogesterone acetate. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2025. [Accessed 02 March. 2025] (online) Available from: View
