Doxinate OD 20mg/20mg Tablet

Doxinate OD 20mg/20mg Tablet is a combination medicine used to treat nausea and vomiting during pregnancy. It prevents the feeling of nausea and sickness in pregnant women. It also provides nutrition to the body.

Take Doxinate OD 20mg/20mg Tablet in the dose and duration prescribed by your doctor. It should be taken on an empty stomach, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are dizziness, drowsiness, and dry mouth. To cope with the side effects, you should drink plenty of fluids. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicine for any health condition. Avoid drinking alcohol as it can cause excessive dizziness, and also can harm the baby in the womb. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery and also follow a healthy diet. To avoid nausea and vomiting during pregnancy, you may drink lemon-infused water. You can also add a salad sprinkled with black salt to your diet. Visit your doctor regularly for laboratory and diagnostic tests as advised.

Treatment of Nausea and vomiting in pregnancy

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxinate OD 20mg/20mg Tablet is to be taken empty stomach.

Doxinate OD 20mg/20mg Tablet is a combination of two medicines: doxylamine and vitamin B6 (pyridoxine). It helps treat nausea and vomiting associated with pregnancy. Doxylamine is an antihistamine that works by blocking the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B that possesses anti-nausea properties.

Q: What if you forget to take Doxinate Tablet?
A: If you miss a dose of Doxinate OD 20mg/20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Take it on an empty stomach with a glass of water.

Doxinate OD 20mg/20mg Tablet may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.

Do not take Doxinate OD 20mg/20mg Tablet with other sedating medications such as those for cough and cold as the combination could worsen dizziness leading to falls or other accidents.

Q. What is Doxinate OD 20mg/20mg Tablet?

Doxinate OD 20mg/20mg Tablet is a combination of two medicines: doxylamine and vitamin B6. This medicine is used to treat nausea and vomiting in pregnant women whose symptoms have not improved after changing their diet or using other non-medication treatments. Doxylamine works by blocking the action of certain natural substances in the body that may cause nausea and vomiting. Vitamin B6 (pyridoxine) is given as the deficiency of vitamin B6 in the body could also be a factor in causing nausea and vomiting during pregnancy.

Q. Can the use of Doxinate OD 20mg/20mg Tablet cause drowsiness or sleepiness?

Yes, one of the common side effects of Doxinate OD 20mg/20mg Tablet is drowsiness. Do not drive, operate heavy machinery, or engage in other activities that need your full attention. Do not drink alcohol or take any medicines that may depress the central nervous system, like cough and cold medicines, certain pain medicines, and medicines that help you sleep, while you are taking Doxinate OD 20mg/20mg Tablet. Severe drowsiness can happen or become worse and may cause falls or accidents.

Q. Are there any specific contraindications associated with the use of Doxinate OD 20mg/20mg Tablet?

The use of Doxinate OD 20mg/20mg Tablet is considered harmful for patients with known allergies to any of the components or excipients of this medicine. Tell your doctor about all of your medical conditions before taking Doxinate OD 20mg/20mg Tablet.

Q. Can I breastfeed while taking Doxinate OD 20mg/20mg Tablet?

No, it is not advisable to breastfeed while using Doxinate OD 20mg/20mg Tablet. This medicine can pass into the breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.

Q. Can I take a higher dose than the recommended dose of this medicine?

No, taking a higher dose than the recommended dose of Doxinate OD 20mg/20mg Tablet can cause increased side effects. If you are experiencing increased severity of nausea or vomiting that is not relieved by the recommended doses, please consult your doctor for reevaluation.

Q. What is the storage condition for the Doxinate OD 20mg/20mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

In Treatment of Nausea and vomiting in pregnancy

Doxinate OD 20mg/20mg Tablet blocks the action of chemicals in the body that can make you feel or be sick during pregnancy. This medicine helps you cope with nausea or vomiting that occurs due to hormonal changes during pregnancy and helps you complete the term without much discomfort. It is a very safe and effective medicine. It also contains a vitamin supplement that improves your baby’s immune system as well as brain development and helps reduce nausea and vomiting during pregnancy.

Dryness in mouth

Lightheadedness

Drowsiness

Alcohol:CAUTION

Caution is advised when consuming alcohol with Doxinate OD 20mg/20mg Tablet. Please consult your doctor.

Pregnancy:SAFE IF PRESCRIBED

Doxinate OD 20mg/20mg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding:CONSULT YOUR DOCTOR

Doxinate OD 20mg/20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:UNSAFE

Doxinate OD 20mg/20mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:SAFE IF PRESCRIBED

Doxinate OD 20mg/20mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Doxinate OD 20mg/20mg Tablet may not be needed in these patients. Please consult your doctor.

Liver:CONSULT YOUR DOCTOR

There is limited information available on the use of Doxinate OD 20mg/20mg Tablet in patients with liver disease. Please consult your doctor.

Matok I, Clark S, Caritis S, et al. Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs. J Clin Pharmacol. 2014;54(12):1429-33. [Accessed 09 Apr. 2019] (online) Availoable from: View
Doxylamine succinate and pyridoxine hydrochloride [Prescribing Information]. Bryn Mawr, PA: Duchesnay USA, Inc.; 2013. [Accessed 22 Aug. 2024] (online) Available from: View
Doxylamine succinate, Pyridoxine hydrochloride [Product Monograph]. Toronto, Ontario: Apotex Inc.; 2024. [Accessed 06 Mar. 2025] (online) Available from: View
Doxylamine succinate, Pyridoxine hydrochloride [Summary of Product Characteristics]. Guadalajara, Spain: Exeltis Healthcare S.L.; 2024. [Accessed 06 Mar. 2025] (online) Available from: View